Perspectives of Molecularly Imprinted Polymer-Based Drug Delivery Systems in Ocular Therapy.
controlled release
drug delivery systems
eye diseases
functional polymers
molecularly imprinted polymers
Journal
Polymers
ISSN: 2073-4360
Titre abrégé: Polymers (Basel)
Pays: Switzerland
ID NLM: 101545357
Informations de publication
Date de publication:
23 Oct 2021
23 Oct 2021
Historique:
received:
29
09
2021
revised:
19
10
2021
accepted:
20
10
2021
entrez:
13
11
2021
pubmed:
14
11
2021
medline:
14
11
2021
Statut:
epublish
Résumé
Although the human eye is an easily accessible sensory organ, it remains a challenge for drug administration due to the presence of several anatomical and physiological barriers which limit the access of drugs to its internal structures. Molecular imprinting technology may be considered the avant-garde approach in advanced drug delivery applications and, in particular, in ocular therapy. In fact, molecularly imprinted polymers hold the promise to compensate for the current shortcomings of the available arsenal of drug delivery systems intended for ocular therapy. The present manuscript aims to review the recent advances, the current challenges and most importantly to raise awareness on the underexplored potential and future perspectives of molecularly imprinted polymer-based drug delivery systems intended for the treatment of eye diseases.
Identifiants
pubmed: 34771205
pii: polym13213649
doi: 10.3390/polym13213649
pmc: PMC8588458
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : Romanian Ministry of Education and Research, CCCDI - UEFISCDI
ID : project number PN-III-P2-2.1-PED-2019-1288, within PNCDI III
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