Microgravity × Radiation: A Space Mechanobiology Approach Toward Cardiovascular Function and Disease.
cardiac disease
cardiovascular
mechanobiology
mechanotransduction
microgravity
radiation
Journal
Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250
Informations de publication
Date de publication:
2021
2021
Historique:
received:
31
07
2021
accepted:
11
10
2021
entrez:
15
11
2021
pubmed:
16
11
2021
medline:
16
11
2021
Statut:
epublish
Résumé
In recent years, there has been an increasing interest in space exploration, supported by the accelerated technological advancements in the field. This has led to a new potential environment that humans could be exposed to in the very near future, and therefore an increasing request to evaluate the impact this may have on our body, including health risks associated with this endeavor. A critical component in regulating the human pathophysiology is represented by the cardiovascular system, which may be heavily affected in these extreme environments of microgravity and radiation. This mini review aims to identify the impact of microgravity and radiation on the cardiovascular system. Being able to understand the effect that comes with deep space explorations, including that of microgravity and space radiation, may also allow us to get a deeper understanding of the heart and ultimately our own basic physiological processes. This information may unlock new factors to consider with space exploration whilst simultaneously increasing our knowledge of the cardiovascular system and potentially associated diseases.
Identifiants
pubmed: 34778261
doi: 10.3389/fcell.2021.750775
pmc: PMC8586646
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
750775Informations de copyright
Copyright © 2021 Basirun, Ferlazzo, Howell, Liu, Middleton, Martinac, Narayanan, Poole, Gentile and Chou.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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