New Antagonists of the Membrane Androgen Receptor OXER1 from the ZINC Natural Product Database.
Journal
ACS omega
ISSN: 2470-1343
Titre abrégé: ACS Omega
Pays: United States
ID NLM: 101691658
Informations de publication
Date de publication:
09 Nov 2021
09 Nov 2021
Historique:
received:
28
07
2021
accepted:
13
09
2021
entrez:
15
11
2021
pubmed:
16
11
2021
medline:
16
11
2021
Statut:
epublish
Résumé
OXER1 (oxoeicosanoid receptor 1) was deorphanized in 1993 and found to be the specific receptor for the arachidonic acid metabolite 5-oxo-ETE. Recently, we have reported that androgen binds to this receptor also, being a membrane androgen receptor, triggering a number of its membrane-mediated actions (cell migration, apoptosis, cell proliferation, Ca
Identifiants
pubmed: 34778638
doi: 10.1021/acsomega.1c04027
pmc: PMC8582029
doi:
Types de publication
Journal Article
Langues
eng
Pagination
29664-29674Informations de copyright
© 2021 The Authors. Published by American Chemical Society.
Déclaration de conflit d'intérêts
The authors declare no competing financial interest.
Références
Exp Cell Res. 2005 Oct 1;309(2):329-39
pubmed: 16038899
J Comput Chem. 2004 Oct;25(13):1605-12
pubmed: 15264254
Prostaglandins Other Lipid Mediat. 2009 Sep;89(3-4):98-104
pubmed: 19450703
Endocrinology. 2019 Apr 1;160(4):772-781
pubmed: 30753403
Sci Rep. 2017 Mar 03;7:42717
pubmed: 28256516
Adv Drug Deliv Rev. 2001 Mar 1;46(1-3):3-26
pubmed: 11259830
Bioorg Med Chem. 2018 Jul 23;26(12):3580-3587
pubmed: 29866479
Mol Cell Biochem. 2019 Nov;461(1-2):37-46
pubmed: 31292831
J Biol Chem. 2002 Aug 30;277(35):31459-65
pubmed: 12065583
Cell Death Dis. 2018 Jul 23;9(8):804
pubmed: 30038429
Nucleic Acids Res. 2013 Jul;41(Web Server issue):W384-8
pubmed: 23737448
J Immunol. 2010 Dec 1;185(11):6413-9
pubmed: 21084670
J Biol Chem. 1993 May 5;268(13):9280-6
pubmed: 8387490
Adv Drug Deliv Rev. 2016 Jun 1;101:89-98
pubmed: 27182629
Plant Cell. 1996 Oct;8(10):1855-1869
pubmed: 12239367
Mol Cancer Ther. 2006 May;5(5):1342-51
pubmed: 16731768
Nat Biotechnol. 2007 Feb;25(2):197-206
pubmed: 17287757
Biochem Biophys Res Commun. 2006 Jan 6;339(1):93-8
pubmed: 16289380
J Pharmacol Exp Ther. 2011 Apr;337(1):24-32
pubmed: 21205921
Trends Biochem Sci. 1997 Jan;22(1):1-2
pubmed: 9020581
J Bacteriol. 2001 Nov;183(21):6454-65
pubmed: 11591691
Steroids. 2019 Feb;142:100-108
pubmed: 30707908
Nucleic Acids Res. 2010 Jul;38(Web Server issue):W445-9
pubmed: 20444869
Metabolism. 2018 Aug;85:348-360
pubmed: 29462574
Mol Cell Endocrinol. 2021 Jan 15;520:111080
pubmed: 33189865
Nat Rev Drug Discov. 2017 Jan;16(1):19-34
pubmed: 27910877
J Clin Endocrinol Metab. 2005 Feb;90(2):893-903
pubmed: 15585562
Mol Pharmacol. 2003 Mar;63(3):471-7
pubmed: 12606753
Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W465-9
pubmed: 18424797
Mol Oncol. 2010 Apr;4(2):135-49
pubmed: 20189893
Proteins. 2019 Dec;87(12):1141-1148
pubmed: 31602685
Proteins. 2004 May 1;55(2):288-304
pubmed: 15048822
J Chem Inf Model. 2008 Nov;48(11):2207-13
pubmed: 18956833
Nature. 2020 Jan;577(7792):706-710
pubmed: 31942072
Nucleic Acids Res. 2016 Jul 8;44(W1):W502-6
pubmed: 27131365
Bioinformatics. 2013 Oct 15;29(20):2588-95
pubmed: 23975762
Biochem Biophys Res Commun. 2005 Sep 9;334(4):987-95
pubmed: 16039985
Pharmacol Res Perspect. 2020 Aug;8(4):e00600
pubmed: 32662237
J Chem Inf Model. 2021 May 24;61(5):2283-2293
pubmed: 33938216
Sci Rep. 2017 Mar 14;7:44418
pubmed: 28290516
Bioinformatics. 2006 Jan 15;22(2):195-201
pubmed: 16301204
J Pharmacol Exp Ther. 2008 May;325(2):698-707
pubmed: 18292294
J Nat Prod. 2012 Jan 27;75(1):2-8
pubmed: 22220635
Science. 2009 Mar 27;323(5922):1718-22
pubmed: 19325113
Clin Pharmacokinet. 2015 Jul;54(7):709-35
pubmed: 25860377
Tumour Biol. 2015 Sep;36(9):6673-5
pubmed: 26282004
Biochim Biophys Acta. 2015 Apr;1851(4):340-55
pubmed: 25449650
Nucleic Acids Res. 2014 Jul;42(Web Server issue):W252-8
pubmed: 24782522
Arch Pharm (Weinheim). 2009 Oct;342(10):584-90
pubmed: 19714673
J Cheminform. 2011 Oct 07;3:33
pubmed: 21982300
Mol Inform. 2011 Mar 14;30(2-3):232-40
pubmed: 27466776
J Comput Chem. 2014 May 15;35(13):1036-44
pubmed: 24599647
J Immunol. 1995 Apr 15;154(8):4123-32
pubmed: 7706749
Steroids. 2008 Oct;73(9-10):953-60
pubmed: 18249430
J Chem Inf Model. 2015 Nov 23;55(11):2324-37
pubmed: 26479676
Proteins. 2016 Sep;84 Suppl 1:293-301
pubmed: 26172288
J Med Chem. 2013 May 9;56(9):3725-32
pubmed: 23581530
J Antibiot (Tokyo). 1996 Jun;49(6):519-26
pubmed: 8698633
Nucleic Acids Res. 2016 Jan 4;44(D1):D1054-68
pubmed: 26464438
J Med Chem. 2014 Jan 23;57(2):364-77
pubmed: 24351031
Mol Inform. 2012 Dec;31(11-12):817-35
pubmed: 27476736
Cancer Lett. 2013 Aug 9;336(1):185-95
pubmed: 23643940
Annu Rev Pharmacol Toxicol. 2005;45:477-94
pubmed: 15822186
J Adv Res. 2017 Nov 24;11:33-41
pubmed: 30034874