Evaluation of Coronary Plaques and Stents with Conventional and Photon-counting CT: Benefits of High-Resolution Photon-counting CT.

CT-Spectral Imaging (Dual Energy) Cardiac Phantom Studies Physics Technology Assessment

Journal

Radiology. Cardiothoracic imaging
ISSN: 2638-6135
Titre abrégé: Radiol Cardiothorac Imaging
Pays: United States
ID NLM: 101748663

Informations de publication

Date de publication:
Oct 2021
Historique:
received: 09 04 2021
revised: 30 08 2021
accepted: 30 09 2021
entrez: 15 11 2021
pubmed: 16 11 2021
medline: 16 11 2021
Statut: epublish

Résumé

To compare the performance of energy-integrating detector (EID) CT, photon-counting detector CT (PCCT), and high-resolution PCCT (HR-PCCT) for the visualization of coronary plaques and reduction of stent artifacts in a phantom model. An investigational scanner with EID and PCCT subsystems was used to image a coronary artery phantom containing cylindrical probes simulating different plaque compositions. The phantom was imaged with and without coronary stents using both subsystems. Images were reconstructed with a clinical cardiac kernel and an additional HR-PCCT kernel. Regions of interest were drawn around probes and evaluated for in-plane diameter and a qualitative comparison by expert readers. A linear mixed-effects model was used to compare the diameter results, and a Shrout-Fleiss intraclass correlation coefficient was used to assess consistency in the reader study. Comparing in-plane diameter to the physical dimension for nonstented and stented phantoms, measurements of the HR-PCCT images were more accurate (nonstented: 4.4% ± 1.1 [standard deviation], stented: -9.4% ± 4.6) than EID (nonstented: 15.5% ± 4.0, stented: -19.5% ± 5.8) and PCCT (nonstented: 19.4% ± 2.5, stented: -18.3% ± 4.4). Our analysis of variance found diameter measurements to be different across image groups for both nonstented and stented cases ( Despite increased noise, HR-PCCT images were able to better visualize coronary plaques and reduce stent artifacts compared with EID or PCCT reconstructions.

Identifiants

DOI: 10.1148/ryct.2021210102 PMID: 34778782 PMC: PMC8581588
pubmed: 34778782
doi: 10.1148/ryct.2021210102
pmc: PMC8581588
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e210102

Subventions

Organisme : NIBIB NIH HHS
ID : R01 EB001838
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL131753
Pays : United States
Organisme : Intramural NIH HHS
ID : ZIA HL006220
Pays : United States
Organisme : Intramural NIH HHS
ID : ZID BC011242
Pays : United States

Informations de copyright

2021 by the Radiological Society of North America, Inc.

Déclaration de conflit d'intérêts

Disclosures of conflicts of interest: J.R.R. No relevant relationships. F.F. No relevant relationships. T.R. No relevant relationships. M.N. No relevant relationships. P.S. No relevant relationships. S.M.S. No relevant relationships. W.P.B. No relevant relationships. B.S. No relevant relationships. A.A.M. No relevant relationships. W.F.P. Grants or contracts from Philips and Boston Scientific (Cooperative Research and Development Agreements with NIH). E.C.J. No relevant relationships. E.S. Relationships unrelated to the present publication: GE, Siemens, Imalogix, 12Sigma, SunNuclear, Nanox, Metis Health Analytics, Cambridge University Press, and Wiley and Sons. M.Y.C. No relevant relationships.

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Auteurs

Jayasai R Rajagopal (JR)

Carl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).
ORCID: 0000-0001-8529-5597

Faraz Farhadi (F)

Carl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).
ORCID: 0000-0002-6958-0811

Taylor Richards (T)

Carl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).

Moozhan Nikpanah (M)

Carl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).
ORCID: 0000-0001-7428-0226

Pooyan Sahbaee (P)

Carl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).

Sujata M Shanbhag (SM)

Carl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).

W Patricia Bandettini (WP)

Carl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).
ORCID: 0000-0003-2342-5637

Babak Saboury (B)

Carl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).
ORCID: 0000-0002-8632-6292

Ashkan A Malayeri (AA)

Carl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).
ORCID: 0000-0002-4442-7343

William F Pritchard (WF)

Carl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).
ORCID: 0000-0001-5805-5344

Elizabeth C Jones (EC)

Carl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).

Ehsan Samei (E)

Carl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).
ORCID: 0000-0001-7451-3309

Marcus Y Chen (MY)

Carl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, NC (J.R.R., T.R., E.S.); Department of Radiology and Imaging Sciences, Clinical Center (F.F., M.N., B.S., A.A.M., E.C.J.), Cardiovascular Branch, National Heart, Lung, and Blood Institute (S.M.S., W.P.B., M.Y.C.), and Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center (W.F.P.), National Institutes of Health, 10 Center Dr, Building 10, Room B1D417, Bethesda, MD 20892; and Siemens Medical Solutions USA, Malvern, Pa (P.S.).
ORCID: 0000-0003-0743-9369

Classifications MeSH