Left ventricular vortex analysis by high-frame rate blood speckle tracking echocardiography in healthy children and in congenital heart disease.
-i, indexed to BSA
AV, atrioventricular
BMI, body mass index
BSA, body surface area
BST, blood speckle tracking
Blood speckle imaging
Bpm, beats per minute
CHD, congenital heart disease
CI, correlation index
Congenital
ED, end-diastolic
Echocardiography
Fps, frame per second
Heart defects
ICC, intraclass correlation coefficient
IQR, interquartile range
IVS, interventricular septum
LV, left ventricle/ventricular
LVEDA, left ventricular end-diastolic area
LVEDD, left ventricular end-diastolic dimension
LVEDV, left ventricular end-diastolic volume
LVEF, left ventricular ejection fraction
LVESD, left ventricular end-systolic dimension
LVESV, left ventricular end-systolic volume
LVOT, left ventricular outflow tract
LVPO, CHD involving left ventricle pressure overload
LVSV, left ventricular stroke volume
LVVO, CHD involving left ventricular volume overload
Left ventricle
MV, mitral valve
Pediatrics
RVPO, CHD involving right ventricular pressure overload
RVVO, CHD involving right ventricular volume overload
TGA, transposition of the great arteries
Vortex imaging
Journal
International journal of cardiology. Heart & vasculature
ISSN: 2352-9067
Titre abrégé: Int J Cardiol Heart Vasc
Pays: Ireland
ID NLM: 101649525
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
received:
15
08
2021
revised:
14
10
2021
accepted:
15
10
2021
entrez:
17
11
2021
pubmed:
18
11
2021
medline:
18
11
2021
Statut:
epublish
Résumé
High-frame rate blood speckle tracking (BST) echocardiography is a new technique for the assessment of intracardiac flow. The purpose of this study was to evaluate the characteristics of left ventricular (LV) vortices in healthy children and in those with congenital heart disease (CHD). Characteristics of LV vortices were analyses based on 4-chamber BST images from 118 healthy children (median age 6.84 years, range 0.01-17 years) and 43 children with CHD (median age 0.99 years, range 0.01-14 years). Both groups were compared after propensity matching. Multiple linear regression was used to identify factors that independently influence vortex characteristics. Feasibility of vortex imaging was 93.7% for healthy children and 95.6% for CHD. After propensity matching, there were no overall significant differences in vortex distance to apex, distance to interventricular septum (IVS), height, width, sphericity index, or area. However, multiple regression analysis revealed significant associations of LV morphology with vortex characteristics. Furthermore, CHD involving LV volume overload and CHD involving LV pressure overload were both associated with vortices localized closer to the IVS. LV vortex analysis using high-frame rate BST echocardiography is feasible in healthy children and in those with CHD. As they are associated with LV morphology and are modified in some types of CHD, vortices might yield diagnostic and prognostic value. Future studies are warranted to establish applications of vortex imaging in the clinical setting.
Sections du résumé
BACKGROUND
BACKGROUND
High-frame rate blood speckle tracking (BST) echocardiography is a new technique for the assessment of intracardiac flow. The purpose of this study was to evaluate the characteristics of left ventricular (LV) vortices in healthy children and in those with congenital heart disease (CHD).
METHODS
METHODS
Characteristics of LV vortices were analyses based on 4-chamber BST images from 118 healthy children (median age 6.84 years, range 0.01-17 years) and 43 children with CHD (median age 0.99 years, range 0.01-14 years). Both groups were compared after propensity matching. Multiple linear regression was used to identify factors that independently influence vortex characteristics.
RESULTS
RESULTS
Feasibility of vortex imaging was 93.7% for healthy children and 95.6% for CHD. After propensity matching, there were no overall significant differences in vortex distance to apex, distance to interventricular septum (IVS), height, width, sphericity index, or area. However, multiple regression analysis revealed significant associations of LV morphology with vortex characteristics. Furthermore, CHD involving LV volume overload and CHD involving LV pressure overload were both associated with vortices localized closer to the IVS.
CONCLUSIONS
CONCLUSIONS
LV vortex analysis using high-frame rate BST echocardiography is feasible in healthy children and in those with CHD. As they are associated with LV morphology and are modified in some types of CHD, vortices might yield diagnostic and prognostic value. Future studies are warranted to establish applications of vortex imaging in the clinical setting.
Identifiants
pubmed: 34786451
doi: 10.1016/j.ijcha.2021.100897
pii: S2352-9067(21)00185-8
pmc: PMC8579140
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100897Informations de copyright
© 2021 The Authors.
Déclaration de conflit d'intérêts
The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: S. Kutty is consultant for GE Healthcare. All other authors declare that they have no competing interests.
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