Bartonella spp. seroepidemiology and associations with clinicopathologic findings in dogs in the United States.
bartonellosis
canine
seroreactivity
vector-borne
zoonoses
Journal
Journal of veterinary internal medicine
ISSN: 1939-1676
Titre abrégé: J Vet Intern Med
Pays: United States
ID NLM: 8708660
Informations de publication
Date de publication:
Jan 2022
Jan 2022
Historique:
revised:
28
10
2021
received:
30
11
2020
accepted:
03
11
2021
pubmed:
18
11
2021
medline:
27
1
2022
entrez:
17
11
2021
Statut:
ppublish
Résumé
Improved understanding of Bartonella spp. serology in dogs may aid clinical decision making. Describe demographic and geographic patterns of Bartonella spp. seroreactivity in dogs, and describe hematologic and serum biochemical abnormalities in Bartonella spp. seroreactive and nonseroreactive dogs. Serum samples from 5957 dogs in the United States, previously submitted to IDEXX Reference Laboratories. Serum was tested using 3 indirect ELISAs for B. henselae, B. vinsonii subsp. berkhoffii, and B. koehlerae. Complete blood count and serum biochemistry panel results were reviewed retrospectively. Overall, 6.1% of dogs were Bartonella spp. seroreactive. Toy breeds were less likely to be seroreactive (3.9%) than mixed breeds (7.5%; adjusted odds ratio [aOR], 0.48; 95% confidence interval [CI], 0.32-0.72), and dogs <1 year old were less likely to be seroreactive (3.4%) than dogs 1 to 5.5 years of age (7.3%; aOR, 0.42; 95% CI, 0.23-0.72). Dogs in the West South Central (9.8%) and South Atlantic (8.8%) regions were more likely than dogs elsewhere in the United States to be seroreactive (aOR, 2.22; 95% CI, 1.31-3.87; aOR, 2.44; 95% CI, 1.38-4.36). Demographic and geographic findings for Bartonella spp. exposure were broadly comparable to previously reported patterns.
Sections du résumé
BACKGROUND
BACKGROUND
Improved understanding of Bartonella spp. serology in dogs may aid clinical decision making.
OBJECTIVE
OBJECTIVE
Describe demographic and geographic patterns of Bartonella spp. seroreactivity in dogs, and describe hematologic and serum biochemical abnormalities in Bartonella spp. seroreactive and nonseroreactive dogs.
ANIMALS
METHODS
Serum samples from 5957 dogs in the United States, previously submitted to IDEXX Reference Laboratories.
METHODS
METHODS
Serum was tested using 3 indirect ELISAs for B. henselae, B. vinsonii subsp. berkhoffii, and B. koehlerae. Complete blood count and serum biochemistry panel results were reviewed retrospectively.
RESULTS
RESULTS
Overall, 6.1% of dogs were Bartonella spp. seroreactive. Toy breeds were less likely to be seroreactive (3.9%) than mixed breeds (7.5%; adjusted odds ratio [aOR], 0.48; 95% confidence interval [CI], 0.32-0.72), and dogs <1 year old were less likely to be seroreactive (3.4%) than dogs 1 to 5.5 years of age (7.3%; aOR, 0.42; 95% CI, 0.23-0.72). Dogs in the West South Central (9.8%) and South Atlantic (8.8%) regions were more likely than dogs elsewhere in the United States to be seroreactive (aOR, 2.22; 95% CI, 1.31-3.87; aOR, 2.44; 95% CI, 1.38-4.36).
CONCLUSIONS AND CLINICAL IMPORTANCE
CONCLUSIONS
Demographic and geographic findings for Bartonella spp. exposure were broadly comparable to previously reported patterns.
Identifiants
pubmed: 34788481
doi: 10.1111/jvim.16311
pmc: PMC8783365
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
116-125Subventions
Organisme : NIH HHS
ID : T32 OD011130
Pays : United States
Organisme : Comparative Medicine and Translational Medicine Research Program of the National Institutes of Health
ID : T32OD011130
Informations de copyright
© 2021 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine.
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