Noncoding RNAs: biology and applications-a Keystone Symposia report.


Journal

Annals of the New York Academy of Sciences
ISSN: 1749-6632
Titre abrégé: Ann N Y Acad Sci
Pays: United States
ID NLM: 7506858

Informations de publication

Date de publication:
12 2021
Historique:
received: 06 10 2021
accepted: 06 10 2021
pubmed: 19 11 2021
medline: 9 2 2022
entrez: 18 11 2021
Statut: ppublish

Résumé

The human transcriptome contains many types of noncoding RNAs, which rival the number of protein-coding species. From long noncoding RNAs (lncRNAs) that are over 200 nucleotides long to piwi-interacting RNAs (piRNAs) of only 20 nucleotides, noncoding RNAs play important roles in regulating transcription, epigenetic modifications, translation, and cell signaling. Roles for noncoding RNAs in disease mechanisms are also being uncovered, and several species have been identified as potential drug targets. On May 11-14, 2021, the Keystone eSymposium "Noncoding RNAs: Biology and Applications" brought together researchers working in RNA biology, structure, and technologies to accelerate both the understanding of RNA basic biology and the translation of those findings into clinical applications.

Identifiants

pubmed: 34791665
doi: 10.1111/nyas.14713
pmc: PMC9808899
mid: NIHMS1747135
doi:

Substances chimiques

MicroRNAs 0
RNA, Long Noncoding 0
RNA, Small Interfering 0
RNA, Small Untranslated 0
RNA, Untranslated 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

118-141

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM132458
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM119735
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA215491
Pays : United States
Organisme : NIA NIH HHS
ID : R21 AG065748
Pays : United States
Organisme : NCI NIH HHS
ID : F99 CA253732
Pays : United States
Organisme : NCI NIH HHS
ID : K00 CA253732
Pays : United States
Organisme : NINDS NIH HHS
ID : R35 NS111631
Pays : United States

Commentaires et corrections

Type : ErratumIn

Informations de copyright

© 2021 New York Academy of Sciences.

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Auteurs

Jennifer Cable (J)

PhD Science Writer, New York, New York.

Edith Heard (E)

European Molecular Biology Laboratory (EMBL), Heidelberg, Heidelberg, Germany.
Collège de France, Paris, France.

Tetsuro Hirose (T)

Graduate School of Frontier Biosciences, Osaka University, Suita, Japan.
Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan.

Kannanganattu V Prasanth (KV)

Department of Cell and Developmental Biology, Cancer Center at Illinois, University of Illinois at Urbana-Champaign, Urbana, Illinois.

Ling-Ling Chen (LL)

State Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of the Chinese Academy of Sciences, Shanghai, China.
School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
School of Life Sciences, Hangzhou Institute for Advanced Study, University of the Chinese Academy of Sciences, Hangzhou, China.

Jonathan E Henninger (JE)

Whitehead Institute for Biomedical Research, Cambridge, Massachusetts.

Sofia A Quinodoz (SA)

Department of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey.

David L Spector (DL)

Cold Spring Harbor Laboratory, Cold Spring Harbor and Genetics Program, Stony Brook University, Stony Brook, New York.

Sarah D Diermeier (SD)

Department of Biochemistry, University of Otago, Dunedin, New Zealand.

Allison M Porman (AM)

Biochemistry and Molecular Genetics Department, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.

Dhiraj Kumar (D)

Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Mark W Feinberg (MW)

Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

Xiaohua Shen (X)

Tsinghua-Peking Joint Center for Life Sciences, School of Medicine and School of Life Sciences, Tsinghua University, Beijing, China.

Juan Pablo Unfried (JP)

Center for Applied Medical Research (CIMA), Department of Gene Therapy and Regulation of Gene Expression, Universidad de Navarra (UNAV), Pamplona, Spain.

Rory Johnson (R)

Department of Medical Oncology, Inselspital, Bern University Hospital; and Department for BioMedical Research University of Bern, Bern, Switzerland.
School of Biology and Environmental Science and Conway Institute for Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.

Chun-Kan Chen (CK)

Center for Personal Dynamic Regulomes, Stanford University, Stanford, California.
Department of Genetics, Stanford University School of Medicine, Stanford, California.

Jeremy E Wilusz (JE)

Department of Biochemistry and Biophysics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

Adelheid Lempradl (A)

Department of Metabolism and Nutritional Programming, Van Andel Research Institute, Grand Rapids, Michigan.

Sean E McGeary (SE)

Whitehead Institute for Biomedical Research, Cambridge, Massachusetts.
Howard Hughes Medical Institute and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts.

Lamia Wahba (L)

Department of Genetics, Stanford University School of Medicine, Stanford, California.
Department of Pathology, Stanford University School of Medicine, Stanford, California.

Anna Marie Pyle (AM)

Department of Genetics, Yale School of Medicine, New Haven, Connecticut.
Connecticut and Howard Hughes Medical Institute, Chevy Chase, Maryland.

Amanda E Hargrove (AE)

Department of Chemistry, Duke University, Durham, North Carolina.

Matthew D Simon (MD)

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut.

Marco Marcia (M)

European Molecular Biology Laboratory (EMBL) Grenoble, Grenoble, France.

Róża K Przanowska (RK)

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia.

Howard Y Chang (HY)

Center for Personal Dynamic Regulomes, Stanford University, Stanford, California.
Howard Hughes Medical Institute, Stanford University, Stanford, California.

Samie R Jaffrey (SR)

Department of Pharmacology, Weill Medical College of Cornell University, New York, New York.

Lydia M Contreras (LM)

McKetta Department of Chemical Engineering, University of Texas at Austin, Austin, Texas.

Qi Chen (Q)

Division of Biomedical Sciences, School of Medicine, University of California, Riverside, Riverside, California.

Junchao Shi (J)

Division of Biomedical Sciences, School of Medicine, University of California, Riverside, Riverside, California.

Joshua T Mendell (JT)

Department of Molecular Biology, Harold C. Simmons Comprehensive Cancer Center, Hamon Center for Regenerative Science and Medicine; and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas.

Lin He (L)

Division of Cellular and Developmental Biology, Molecular and Cell Biology Department, University of California at Berkeley, Berkeley, California.

Erwei Song (E)

Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center and Breast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University; Bioland Laboratory; Program of Molecular Medicine, Zhongshan School of Medicine, Sun Yat-sen University; and Fountain-Valley Institute for Life Sciences, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences Guangzhou, Guangzhou, China.

John L Rinn (JL)

Department of Biochemistry, BioFrontiers Institute, and Howard Hughes Medical Institute, University of Colorado Boulder, Boulder, Colorado.

Mukesh Kumar Lalwani (MK)

Queens Medical Research Institute, BHF Centre for Cardiovascular Sciences, University of Edinburgh, Scotland, United Kingdom.

Murat Can Kalem (MC)

Department of Microbiology and Immunology, Witebsky Center for Microbial Pathogenesis and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, SUNY, Buffalo, New York.

Edward B Chuong (EB)

Department of Molecular, Cellular, and Developmental Biology and BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado.

Lynne E Maquat (LE)

Department of Biochemistry and Biophysics, School of Medicine and Dentistry and Center for RNA Biology, University of Rochester, Rochester, New York.

Xuhang Liu (X)

Laboratory of Systems Cancer Biology, The Rockefeller University, New York, New York.

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