Intra- and inter-fraction relative range verification in heavy-ion therapy using filtered interaction vertex imaging.
heavy-ion therapy
interaction vertex imaging
range monitoring
silicon detectors
Journal
Physics in medicine and biology
ISSN: 1361-6560
Titre abrégé: Phys Med Biol
Pays: England
ID NLM: 0401220
Informations de publication
Date de publication:
16 12 2021
16 12 2021
Historique:
received:
07
06
2021
accepted:
18
11
2021
pubmed:
19
11
2021
medline:
4
5
2022
entrez:
18
11
2021
Statut:
epublish
Résumé
Heavy-ion therapy, particularly using scanned (active) beam delivery, provides a precise and highly conformal dose distribution, with maximum dose deposition for each pencil beam at its endpoint (Bragg peak), and low entrance and exit dose. To take full advantage of this precision, robust range verification methods are required; these methods ensure that the Bragg peak is positioned correctly in the patient and the dose is delivered as prescribed. Relative range verification allows intra-fraction monitoring of Bragg peak spacing to ensure full coverage with each fraction, as well as inter-fraction monitoring to ensure all fractions are delivered consistently. To validate the proposed filtered interaction vertex imaging (IVI) method for relative range verification, a
Identifiants
pubmed: 34794127
doi: 10.1088/1361-6560/ac3b33
doi:
Substances chimiques
Polymethyl Methacrylate
9011-14-7
Silicon
Z4152N8IUI
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2021 Institute of Physics and Engineering in Medicine.