Cardiovascular Health in Pediatric Rheumatologic Diseases.

Cardiovascular disease Cardiovascular health Juvenile dermatomyositis Juvenile idiopathic arthritis Pediatric rheumatology Systemic lupus erythematosus

Journal

Rheumatic diseases clinics of North America
ISSN: 1558-3163
Titre abrégé: Rheum Dis Clin North Am
Pays: United States
ID NLM: 8708093

Informations de publication

Date de publication:
02 2022
Historique:
entrez: 20 11 2021
pubmed: 21 11 2021
medline: 15 12 2021
Statut: ppublish

Résumé

Cardiovascular disease risk is evident during childhood for patients with juvenile systemic lupus erythematosus, juvenile dermatomyositis, and juvenile idiopathic arthritis. The American Heart Association defines cardiovascular health as a positive health construct reflecting the sum of protective factors against cardiovascular disease. Disease-related factors such as chronic inflammation and endothelial dysfunction increase cardiovascular disease risk directly and through bidirectional relationships with poor cardiovascular health factors. Pharmacologic and nonpharmacologic interventions to improve cardiovascular health and long-term cardiovascular outcomes in children with rheumatic disease are needed.

Identifiants

pubmed: 34798945
pii: S0889-857X(21)01131-5
doi: 10.1016/j.rdc.2021.09.006
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

157-181

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure Dr K. Ardalan receives salary support from Cure JM Foundation to assist with clinical trial design with ReveraGen BioPharma but does not receive any funding or compensation from ReveraGen BioPharma; he also receives salary/grant support from the Childhood Arthritis and Rheumatology Research Alliance (CARRA) and Rheumatology Research Foundation. Dr D.M. Lloyd-Jones has no commercial or financial conflicts to disclose. Dr L.E. Schanberg receives salary support from CARRA, Inc; DSMB member for Sanofi and UCB; grant support from PCORI and BMS.

Auteurs

Kaveh Ardalan (K)

Department of Pediatrics, Division of Pediatric Rheumatology, Duke University School of Medicine, T909 Children's Health Center, DUMC Box 3212, Durham, NC 27710, USA; Department of Pediatrics, Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago; Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago. Electronic address: kaveh.ardalan@duke.edu.

Donald M Lloyd-Jones (DM)

Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Suite 1400, 680 North Lake Shore Drive, Chicago, IL 60611, USA; Department of Medicine, Northwestern University Feinberg School of Medicine, Suite 1400, 680 North Lake Shore Drive, Chicago, IL 60611, USA; Department of Pediatrics, Northwestern University Feinberg School of Medicine, Suite 1400, 680 North Lake Shore Drive, Chicago, IL 60611, USA.

Laura E Schanberg (LE)

Department of Pediatrics, Division of Pediatric Rheumatology, Duke Clinical Research Institute, Duke University School of Medicine, T909 Children's Health Center, DUMC Box 3212, Durham, NC 27710, USA.

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Classifications MeSH