Enzymatic synthesis and formation kinetics of mono- and di-hydroxylated chlorinated paraffins with the bacterial dehalogenase LinB from Sphingobium indicum.

Dihydroxylated chloroparaffins (CP-diols) Enzymatic dehalohydroxylation Hydroxylated chloroparaffins (CP-ols) In-vitro CP transformation Persistent organic pollutants (POPs)

Journal

Chemosphere
ISSN: 1879-1298
Titre abrégé: Chemosphere
Pays: England
ID NLM: 0320657

Informations de publication

Date de publication:
Mar 2022
Historique:
received: 27 06 2021
revised: 11 11 2021
accepted: 14 11 2021
pubmed: 21 11 2021
medline: 27 1 2022
entrez: 20 11 2021
Statut: ppublish

Résumé

Transformation studies of chlorinated paraffins (CPs) and the effects of CP transformation products on humans, biota and environment are rare. The focus here is on hydroxylation reactions. As for polyhalogenated persistent organic pollutants (POPs) in general, hydroxylation reactions convert lipophilic material to more polar compounds with increased mobility. We investigated the in-vitro transformation of single-chain CP-mixtures to hydroxylated products with the dehalogenase LinB from Sphingobium indicum. C

Identifiants

pubmed: 34800506
pii: S0045-6535(21)03411-1
doi: 10.1016/j.chemosphere.2021.132939
pii:
doi:

Substances chimiques

Hydrocarbons, Chlorinated 0
Paraffin 8002-74-2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

132939

Informations de copyright

Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved.

Auteurs

Marco C Knobloch (MC)

Laboratory for Advanced Analytical Technologies, Swiss Federal Institute for Materials Science and Technology Empa, Überlandstrasse 129, 8600, Dübendorf, Switzerland; Department of Chemistry, University of Zürich, Winterthurerstrasse 190, 8057, Zürich, Switzerland. Electronic address: marco.knobloch@empa.ch.

Flurin Mathis (F)

Laboratory for Advanced Analytical Technologies, Swiss Federal Institute for Materials Science and Technology Empa, Überlandstrasse 129, 8600, Dübendorf, Switzerland; Zürich University of Applied Sciences ZHAW, Einsiedlerstrasse 31, 8820, Wädenswil, Switzerland.

Thomas Fleischmann (T)

Swiss Federal Institute of Aquatic Research and Technology Eawag, Überlandstrasse 129, 8600, Dübendorf, Switzerland.

Hans-Peter E Kohler (HE)

Swiss Federal Institute of Aquatic Research and Technology Eawag, Überlandstrasse 129, 8600, Dübendorf, Switzerland.

Susanne Kern (S)

Zürich University of Applied Sciences ZHAW, Einsiedlerstrasse 31, 8820, Wädenswil, Switzerland.

Davide Bleiner (D)

Laboratory for Advanced Analytical Technologies, Swiss Federal Institute for Materials Science and Technology Empa, Überlandstrasse 129, 8600, Dübendorf, Switzerland; Department of Chemistry, University of Zürich, Winterthurerstrasse 190, 8057, Zürich, Switzerland.

Norbert V Heeb (NV)

Laboratory for Advanced Analytical Technologies, Swiss Federal Institute for Materials Science and Technology Empa, Überlandstrasse 129, 8600, Dübendorf, Switzerland.

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Classifications MeSH