Persistent Expression of Recipient-type ABH Antigen after ABO-incompatible Allogeneic Hematopoietic Stem Cell Transplantation.
ABO blood group antigen
ABO-incompatibility
allogeneic HSCT
blood type
transfusion
Journal
Internal medicine (Tokyo, Japan)
ISSN: 1349-7235
Titre abrégé: Intern Med
Pays: Japan
ID NLM: 9204241
Informations de publication
Date de publication:
15 Jun 2022
15 Jun 2022
Historique:
pubmed:
23
11
2021
medline:
18
6
2022
entrez:
22
11
2021
Statut:
ppublish
Résumé
In general, the recipient's ABO blood type changes to the donor's ABO blood type after ABO-incompatible allogeneic hematopoietic stem cell transplantation (HSCT). However, we experienced a 26-year-old male with acute myelogenous leukemia (AML) who underwent ABO-incompatible HSCT twice and persistently showed his original blood type even after demonstrating complete donor-type chimerism. Based on the results of various examinations, we considered that the antigen of the recipient's original blood type persistently synthesized in the recipient's non-hematopoietic organs was secreted and adsorbed on the surface of donor-derived RBCs. We should therefore perform detailed examinations to determine the precise blood type after ABO-incompatible HSCT.
Identifiants
pubmed: 34803100
doi: 10.2169/internalmedicine.8315-21
pmc: PMC9259807
doi:
Substances chimiques
ABO Blood-Group System
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1887-1890Références
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