A Rare Case of Trichilemmal Carcinoma: Histology and Management.
Trichilemmal carcinoma
adnexal tumor
clear cell
outer root sheath
trichilemmal keratinization
Journal
The Journal of clinical and aesthetic dermatology
ISSN: 1941-2789
Titre abrégé: J Clin Aesthet Dermatol
Pays: United States
ID NLM: 101518173
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
entrez:
22
11
2021
pubmed:
23
11
2021
medline:
23
11
2021
Statut:
ppublish
Résumé
Trichilemmal carcinoma (TC) is a rare cutaneous tumor thought to be derived from the follicular outer root sheath (ORS). It often manifests as a nondescript skin-colored or pink papule on the hair-bearing, sun-exposed anatomic sites of elderly patients. Trichilemmal carcinoma shows many histologic features reminiscent of follicular ORS-notably, its glycogen-rich clear cells, trichilemmal keratinization, and similar immunostaining profile. Historically, it has been described as following a relatively indolent clinical course, but cases of recurrence, local aggression, and distant metastases have recently been elucidated. Here, we report the case of a 66-year-old male patient who presented with an asymptomatic, erythematous plaque on his neck; biopsy confirmed a diagnosis of TC. The patient deferred Mohs micrographic surgery in favor of wide local excision and was treated successfully with 3-mm margins. Salient histopathologic features, treatment modalities, and management recommendations are discussed.
Types de publication
Case Reports
Langues
eng
Pagination
25-30Informations de copyright
Copyright © 2021. Matrix Medical Communications. All rights reserved.
Déclaration de conflit d'intérêts
DISCLOSURES: The authors report no conflicts of interest relevant to the content of this article..
Références
J Cutan Pathol. 2007 May;34(5):381-5
pubmed: 17448192
Am J Pathol. 1976 Nov;85(2):479-514
pubmed: 793411
Saudi J Ophthalmol. 2017 Jul-Sep;31(3):183-185
pubmed: 28860920
Am J Dermatopathol. 1994 Oct;16(5):463-73
pubmed: 7528473
J Am Acad Dermatol. 2015 Jan;72(1):195-6
pubmed: 25497926
Am J Dermatopathol. 2008 Aug;30(4):333-9
pubmed: 18645304
Am J Surg Pathol. 1980 Dec;4(6):573-83
pubmed: 6163367
Korean J Ophthalmol. 2009 Dec;23(4):301-5
pubmed: 20046693
World J Oncol. 2018 Nov;9(5-6):141-144
pubmed: 30524638
Acta Histochem. 2019 Aug;121(6):765-767
pubmed: 31230705
Oncol Lett. 2014 Feb;7(2):423-426
pubmed: 24396460
Transplant Proc. 2015 Jan-Feb;47(1):155-7
pubmed: 25645796
Cancer Res Treat. 2010 Sep;42(3):176-9
pubmed: 20948924
Dermatol Surg. 2005 Aug;31(8 Pt 1):973-6
pubmed: 16042947
Dermatol Surg. 2004 Jan;30(1):113-5
pubmed: 14692940
Hum Pathol. 1998 Feb;29(2):193-5
pubmed: 9490283
Ann Dermatol. 2008 Sep;20(3):157-61
pubmed: 27303183
Cureus. 2018 Nov 19;10(11):e3614
pubmed: 30680270
An Bras Dermatol. 2018 Jul-Aug;93(4):579-581
pubmed: 30066770
Dermatol Surg. 2007 Sep;33(9):1102-8
pubmed: 17760602
Dermatol Surg. 2014 Jul;40(7):711-7
pubmed: 25111341
J Cutan Pathol. 1992 Apr;19(2):94-9
pubmed: 1375954
Mol Clin Oncol. 2013 May;1(3):499-502
pubmed: 24649199
J Cutan Pathol. 1992 Apr;19(2):100-9
pubmed: 1597565
Dermatol Surg. 2017 Oct;43(10):1199-1207
pubmed: 28445202
J Cutan Pathol. 2013 Jun;40(6):532-7
pubmed: 23531053
An Bras Dermatol. 2015 Nov-Dec;90(6):780-96; quiz 797-8
pubmed: 26734858
Ann Dermatol. 2018 Jun;30(3):368-370
pubmed: 29853758
Actas Dermosifiliogr. 2012 Jun;103(5):357-75
pubmed: 22463770
J Cutan Pathol. 1993 Feb;20(1):44-9
pubmed: 8468416
Rom J Morphol Embryol. 2014;55(2 Suppl):687-91
pubmed: 25178345
Ann Dermatol. 2010 Aug;22(3):330-2
pubmed: 20711273
Br J Plast Surg. 1999 Dec;52(8):665-7
pubmed: 10658141
Acta Ophthalmol Scand. 2003 Oct;81(5):536-8
pubmed: 14510806
J Dermatol. 2008 Dec;35(12):782-5
pubmed: 19239559
Dermatol Surg. 2003 Aug;29(8):886-9
pubmed: 12859397
J Dermatol. 1996 Jul;23(7):463-8
pubmed: 8772025
Dermatology. 2002;204(4):315-7
pubmed: 12077536
Br J Dermatol. 2000 Sep;143(3):646-7
pubmed: 10971347
J Cutan Pathol. 1994 Jun;21(3):224-8
pubmed: 7525669
J Am Acad Dermatol. 1997 Jan;36(1):107-9
pubmed: 8996274
An Bras Dermatol. 2011 Sep-Oct;86(5):991-4
pubmed: 22147041
Dermatol Surg. 2004 Jul;30(7):1062-4
pubmed: 15209802
BMJ Case Rep. 2013 Apr 18;2013:
pubmed: 23605822