NAD
Journal
NAR cancer
ISSN: 2632-8674
Titre abrégé: NAR Cancer
Pays: England
ID NLM: 101769553
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
received:
26
04
2021
revised:
20
10
2021
accepted:
10
11
2021
entrez:
22
11
2021
pubmed:
23
11
2021
medline:
23
11
2021
Statut:
epublish
Résumé
Elevated expression of the DNA damage response proteins PARP1 and poly(ADP-ribose) glycohydrolase (PARG) in glioma stem cells (GSCs) suggests that glioma may be a unique target for PARG inhibitors (PARGi). While PARGi-induced cell death is achieved when combined with ionizing radiation, as a single agent PARG inhibitors appear to be mostly cytostatic. Supplementation with the NAD
Identifiants
pubmed: 34806016
doi: 10.1093/narcan/zcab044
pii: zcab044
pmc: PMC8600031
doi:
Types de publication
Journal Article
Langues
eng
Pagination
zcab044Subventions
Organisme : NCI NIH HHS
ID : R01 CA148629
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA238061
Pays : United States
Organisme : NIEHS NIH HHS
ID : U01 ES029518
Pays : United States
Informations de copyright
© The Author(s) 2021. Published by Oxford University Press on behalf of NAR Cancer.
Références
Cancer Res. 2012 Jun 1;72(11):2814-21
pubmed: 22447567
Nature. 2006 Dec 7;444(7120):756-60
pubmed: 17051156
Nature. 2018 Jul;559(7713):279-284
pubmed: 29950726
Clin Cancer Res. 2009 Aug 15;15(16):5145-53
pubmed: 19671863
Biomolecules. 2020 Sep 16;10(9):
pubmed: 32947956
Nat Struct Mol Biol. 2013 Mar;20(3):347-54
pubmed: 23396353
Exp Cell Res. 1964 Jan;33:301-9
pubmed: 14109144
EMBO J. 2019 Aug 15;38(16):e101379
pubmed: 31267591
Cell Rep. 2014 Sep 25;8(6):1819-1831
pubmed: 25220464
Antioxid Redox Signal. 2011 Jun 15;14(12):2491-507
pubmed: 20649466
Trends Cell Biol. 2020 May;30(5):370-383
pubmed: 32302549
Nature. 2016 Jul 20;535(7612):382-7
pubmed: 27443740
Cancer Res. 2012 Nov 1;72(21):5588-99
pubmed: 23118055
DNA Repair (Amst). 2021 Oct;106:103179
pubmed: 34311273
Nat Commun. 2014 Nov 26;5:5513
pubmed: 25423885
Nature. 2017 Jul 13;547(7662):241-245
pubmed: 28636597
Nat Commun. 2015 Aug 19;6:8088
pubmed: 26286827
Science. 2014 Jan 3;343(6166):84-87
pubmed: 24336571
EMBO J. 2009 Sep 2;28(17):2601-15
pubmed: 19629035
Oncogene. 2010 Sep 9;29(36):5095-102
pubmed: 20581868
Cancer Cell. 2010 Jan 19;17(1):98-110
pubmed: 20129251
Cancer Cell. 2019 Mar 18;35(3):519-533.e8
pubmed: 30889383
Cell Rep. 2021 Nov 2;37(5):109917
pubmed: 34731617
Ann N Y Acad Sci. 2009 Sep;1173 Suppl 1:E10-9
pubmed: 19751409
Cell Rep. 2016 Sep 6;16(10):2641-2650
pubmed: 27568560
Genes Dev. 2020 Mar 1;34(5-6):360-394
pubmed: 32029455
Cell Cycle. 2015;14(2):269-76
pubmed: 25607651
Cancer Discov. 2014 Oct;4(10):1198-213
pubmed: 25100205
Cancer Res. 2015 Oct 15;75(20):4416-28
pubmed: 26282173
Nat Biotechnol. 2013 Sep;31(9):827-32
pubmed: 23873081
Cell Metab. 2012 Sep 5;16(3):290-5
pubmed: 22921416
Nat Commun. 2019 Dec 11;10(1):5654
pubmed: 31827085
Int J Radiat Oncol Biol Phys. 2012 May 1;83(1):e43-52
pubmed: 22516386
Cell Metab. 2014 Nov 4;20(5):706-707
pubmed: 25440052
DNA Repair (Amst). 2017 Apr;52:81-91
pubmed: 28254358
Nat Rev Mol Cell Biol. 2017 Oct;18(10):622-636
pubmed: 28811666
Nat Rev Cancer. 2015 May;15(5):276-89
pubmed: 25907220
Cancers (Basel). 2019 Mar 13;11(3):
pubmed: 30871194
Science. 2011 Jun 17;332(6036):1443-6
pubmed: 21680843
Nat Rev Mol Cell Biol. 2020 Oct;21(10):633-651
pubmed: 32612242
Nature. 2004 Nov 18;432(7015):396-401
pubmed: 15549107
DNA Repair (Amst). 2014 Nov;23:27-32
pubmed: 25283336
Sci Rep. 2020 Jan 20;10(1):651
pubmed: 31959836
Cancer Res. 2019 Sep 1;79(17):4491-4502
pubmed: 31273064
Acta Neurochir (Wien). 2012 Jun;154(6):951-69; discussion 969
pubmed: 22527576
Mol Cell. 2018 Jul 19;71(2):319-331.e3
pubmed: 29983321
Cancer Cell. 2015 Dec 14;28(6):773-784
pubmed: 26678339
Sci Rep. 2018 Feb 9;8(1):2771
pubmed: 29426857
Mol Cell. 2021 Apr 1;81(7):1515-1533.e5
pubmed: 33571423
DNA Repair (Amst). 2007 Jun 1;6(6):695-711
pubmed: 17337257
Biochemistry. 1998 Jun 30;37(26):9363-70
pubmed: 9649317
J Biol Chem. 2017 Feb 10;292(6):2470-2484
pubmed: 28003368
Cancer Res. 2018 Dec 15;78(24):6713-6716
pubmed: 30498082
Pharmacol Res. 2016 Dec;114:274-283
pubmed: 27816507
Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):E2453-61
pubmed: 24927568
Mol Aspects Med. 2013 Dec;34(6):1168-201
pubmed: 23357756
Nat Metab. 2020 Apr;2(4):364-379
pubmed: 32694608
Cancer Res. 2012 Mar 15;72(6):1428-37
pubmed: 22396498
Nucleic Acids Res. 2018 Oct 12;46(18):9537-9549
pubmed: 30137419
Proc Natl Acad Sci U S A. 2013 May 21;110(21):8644-9
pubmed: 23650391
Mutat Res. 2010 Apr 1;686(1-2):57-67
pubmed: 20096707
J Biotechnol. 2015 Aug 20;208:44-53
pubmed: 26003884
Cell. 2014 May 8;157(4):882-896
pubmed: 24813611
Cancer Res. 2011 Mar 15;71(6):2308-17
pubmed: 21406402
J Biol Chem. 2020 Dec 11;295(50):16949-16959
pubmed: 32989049
Nat Methods. 2014 Aug;11(8):783-784
pubmed: 25075903
DNA Repair (Amst). 2018 Jan;61:25-36
pubmed: 29179156
Mol Cancer Res. 2009 Mar;7(3):383-92
pubmed: 19276180
Cancer Res. 2016 Mar 1;76(5):1078-88
pubmed: 26603896
Science. 2017 Mar 24;355(6331):1312-1317
pubmed: 28336669
Biomol Concepts. 2020 Dec 23;11(1):209-220
pubmed: 34233432
Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11597-602
pubmed: 8876181
Nat Commun. 2016 Jul 20;7:12235
pubmed: 27436229
Genes Dev. 2012 Apr 15;26(8):756-84
pubmed: 22508724
Genes Dev. 2019 Jun 1;33(11-12):591-609
pubmed: 31160393
J Cell Biol. 2012 Mar 19;196(6):801-10
pubmed: 22412018
Nat Commun. 2013;4:2993
pubmed: 24356582
Cell Death Differ. 2014 Feb;21(2):258-69
pubmed: 24121277
EMBO J. 2016 Jul 15;35(14):1488-503
pubmed: 27225932
NAR Cancer. 2020 Sep;2(3):zcaa013
pubmed: 32776008
FEBS J. 2016 Jan;283(2):232-45
pubmed: 26507796
Neurochem Res. 2012 Jun;37(6):1192-200
pubmed: 22228201
Mol Metab. 2019 Dec;30:192-202
pubmed: 31767171
Cancer Cell. 2006 Mar;9(3):157-73
pubmed: 16530701
Cell. 2004 May 14;117(4):495-502
pubmed: 15137942
Nat Commun. 2017 Oct 11;8(1):857
pubmed: 29021619
J Biol Chem. 2007 Jun 15;282(24):17845-54
pubmed: 17430886
DNA Repair (Amst). 2020 Sep;93:102930
pubmed: 33087267
Cell Rep. 2019 May 7;27(6):1809-1821.e5
pubmed: 31067465
Trends Biochem Sci. 2010 Apr;35(4):208-19
pubmed: 20106667
J Biol Chem. 1998 Mar 6;273(10):5858-68
pubmed: 9488723
Cancer Res. 2018 Sep 1;78(17):5060-5071
pubmed: 29976574
J Biol Chem. 2019 Jun 7;294(23):9295-9307
pubmed: 30948509
Cancer Discov. 2020 Nov;10(11):1672-1689
pubmed: 32606138
Trends Cancer. 2017 Aug;3(8):593-610
pubmed: 28780936