Magnetic resonance imaging of endolymphatic hydrops in patients with unilateral Meniere's disease: volume ratio and distribution rate of the endolymphatic space.
Endolymphatic hydrops
Meniere’s disease
distribution rate
magnetic resonance imaging
volumetric measurement
Journal
Acta oto-laryngologica
ISSN: 1651-2251
Titre abrégé: Acta Otolaryngol
Pays: England
ID NLM: 0370354
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
pubmed:
23
11
2021
medline:
17
2
2022
entrez:
22
11
2021
Statut:
ppublish
Résumé
Endolymphatic hydrops (ELH), which is a pathological feature of Meniere's disease (MD), is characterized by an extended endolymphatic space (ELS). We aimed to perform a quantitative volumetric analysis of inner-ear ELH in patients with unilateral MD (uMD). This study included 97 patients with definite uMD and 49 control subjects (CS). The ELS/total fluid space (TFS) volume ratio (%) and the distribution rate of the inner-ear components in the ELS (%) were measured using 3D magnetic resonance imaging and compared between patients with uMD and CS. Compared to CS, patients with uMD had significantly higher mean ELS/TFS volume ratios for inner-ear components. The mean distribution rate of the inner-ear components in the ELS was not significantly different between the two groups. In patients with uMD, ELH was noted to be spread throughout the entire inner ear and the endolymph was evenly distributed in the total ELS. These findings should be useful as a standard reference for further research.
Sections du résumé
BACKGROUND
BACKGROUND
Endolymphatic hydrops (ELH), which is a pathological feature of Meniere's disease (MD), is characterized by an extended endolymphatic space (ELS).
AIMS/OBJECTIVES
OBJECTIVE
We aimed to perform a quantitative volumetric analysis of inner-ear ELH in patients with unilateral MD (uMD).
MATERIAL AND METHODS
METHODS
This study included 97 patients with definite uMD and 49 control subjects (CS). The ELS/total fluid space (TFS) volume ratio (%) and the distribution rate of the inner-ear components in the ELS (%) were measured using 3D magnetic resonance imaging and compared between patients with uMD and CS.
RESULTS
RESULTS
Compared to CS, patients with uMD had significantly higher mean ELS/TFS volume ratios for inner-ear components. The mean distribution rate of the inner-ear components in the ELS was not significantly different between the two groups.
CONCLUSIONS AND SIGNIFICANCE
CONCLUSIONS
In patients with uMD, ELH was noted to be spread throughout the entire inner ear and the endolymph was evenly distributed in the total ELS. These findings should be useful as a standard reference for further research.
Identifiants
pubmed: 34807797
doi: 10.1080/00016489.2021.1968488
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM