Expert consensus on drug treatment of chronic subdural hematoma.
Journal
Chinese neurosurgical journal
ISSN: 2057-4967
Titre abrégé: Chin Neurosurg J
Pays: England
ID NLM: 101672561
Informations de publication
Date de publication:
22 Nov 2021
22 Nov 2021
Historique:
received:
13
02
2021
accepted:
22
09
2021
entrez:
23
11
2021
pubmed:
24
11
2021
medline:
24
11
2021
Statut:
epublish
Résumé
Chronic subdural hematoma (CSDH) is a chronic space-occupying lesion formed by blood accumulation between arachnoid and dura mater, which is usually formed in the third week after traumatic brain injury. Surgical treatment is usually the first choice for patients with CSDH having a significant space-occupying effect. Most of the patients showed good results of surgical treatment, but still some patients had a postoperative recurrence (the recurrence rate was up to 33%). Because CSDH is often seen in the elderly, patients are weak and have many basic diseases. The risk of surgical treatment is high; serious complications and even death (the death rate is up to 32%) can often occur. The overall good prognosis rate of patients aged more than 90 years is 24%. The drug treatment can provide a safe and effective treatment for elderly patients who are weak, intolerable to surgery, or failed in surgery. Low-dose and long-term use of atorvastatin (20mg/d) is suggested for continuous treatment for at least 8 weeks, while low-dose and short-term use of dexamethasone can improve the therapeutic effect of atorvastatin on CSDH. Patients should undergo CT or MRI scanning at least one time within 2 weeks after the start of drug treatment.
Identifiants
pubmed: 34809712
doi: 10.1186/s41016-021-00263-z
pii: 10.1186/s41016-021-00263-z
pmc: PMC8607705
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
47Subventions
Organisme : National Natural Science Foundation of China
ID : 81971176
Organisme : National Natural Science Foundation of China
ID : 81720108015
Investigateurs
Zhou Fei
(Z)
Hua Feng
(H)
Guodong Gao
(G)
Jiehe Hao
(J)
Lijun Hou
(L)
Jin Hu
(J)
Ying Huang
(Y)
Baohua Jiao
(B)
Hongming Ji
(H)
Xiaochun Jiang
(X)
Dezhi Kang
(D)
Jianrong Li
(J)
Xingang Li
(X)
Jinfang Liu
(J)
Ning Liu
(N)
Xianzhi Liu
(X)
Ying Mao
(Y)
Yan Qu
(Y)
Wai Sang Poon
(WS)
Ning Su
(N)
Tao Sun
(T)
Xiaochuan Sun
(X)
Jianjun Wang
(J)
Renzhi Wang
(R)
Junji Wei
(J)
Shuo Wang
(S)
Gangfeng Yin
(G)
Chao You
(C)
Rutong Yu
(R)
Xinguang Yu
(X)
Xianrui Yuan
(X)
Jianmin Zhang
(J)
Junyi Zhang
(J)
Shiguang Zhao
(S)
Yuanli Zhao
(Y)
Zongmao Zhao
(Z)
Chunlong Zhong
(C)
Xide Zhu
(X)
Xingen Zhu
(X)
Rongcai Jiang
(R)
Dong Wang
(D)
Ye Tian
(Y)
Huijie Wei
(H)
Wei Quan
(W)
Chuang Gao
(C)
Shuyuan Yue
(S)
Ping Lei
(P)
Quanjun Deng
(Q)
Shu Zhang
(S)
Yuan Zhou
(Y)
Jian Sun
(J)
Shuo An
(S)
Yingsheng Wei
(Y)
Xintong Ge
(X)
Informations de copyright
© 2021. The Author(s).
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