Fetal posterior cerebral artery configurations in an ischemic stroke versus an unselected hospital population.
CTA
MRA
fetal type posterior cerebral artery
ischemic stroke
Journal
Acta neurologica Scandinavica
ISSN: 1600-0404
Titre abrégé: Acta Neurol Scand
Pays: Denmark
ID NLM: 0370336
Informations de publication
Date de publication:
Mar 2022
Mar 2022
Historique:
revised:
04
11
2021
received:
18
08
2021
accepted:
10
11
2021
pubmed:
24
11
2021
medline:
3
2
2022
entrez:
23
11
2021
Statut:
ppublish
Résumé
Few MRA-based studies have systematically evaluated the prevalence and laterality of a fetal configuration of the posterior cerebral artery (FTP) in ischemic stroke populations versus other populations. This common variant is important in the setting of acute stroke and secondary prevention decisions. To determine the prevalence and laterality of FTP configurations in MRI-DWI verified acute ischemic stroke patients investigated with MRA, and compare the findings with an unselected hospital population investigated with computed tomography angiography (CTA). We also evaluated the association of FTP with posterior cerebral artery (PCA) territory infarctions. We reviewed the MRAs of 1407 ischemic stroke patients with acute lesions on MRI-DWI sequences and 546 consecutive CTAs of patients investigated on any indication in a tertiary hospital. The MRA and CTA assessments were made by neuroradiologists blinded to original reports on stroke location and vessel anatomy. The prevalence of any FTP was similar in ischemic stroke patients (31%) and unselected patients (32%). Unilateral FTP was significantly more frequent on the right than on the left side in both groups (15% right vs. 8% left). The presence of FTP ipsilateral to stroke side was not associated with involvement of the PCA territory versus no FTP on the stroke side. FTP is present in approximately 30% of ischemic stroke patients and unselected hospital populations and was detected significantly more frequently on the right versus left side in both groups. PCA territory infarction was not associated with the presence of ipsilateral FTP.
Sections du résumé
BACKGROUND
BACKGROUND
Few MRA-based studies have systematically evaluated the prevalence and laterality of a fetal configuration of the posterior cerebral artery (FTP) in ischemic stroke populations versus other populations. This common variant is important in the setting of acute stroke and secondary prevention decisions.
OBJECTIVE
OBJECTIVE
To determine the prevalence and laterality of FTP configurations in MRI-DWI verified acute ischemic stroke patients investigated with MRA, and compare the findings with an unselected hospital population investigated with computed tomography angiography (CTA). We also evaluated the association of FTP with posterior cerebral artery (PCA) territory infarctions.
METHODS
METHODS
We reviewed the MRAs of 1407 ischemic stroke patients with acute lesions on MRI-DWI sequences and 546 consecutive CTAs of patients investigated on any indication in a tertiary hospital. The MRA and CTA assessments were made by neuroradiologists blinded to original reports on stroke location and vessel anatomy.
RESULTS
RESULTS
The prevalence of any FTP was similar in ischemic stroke patients (31%) and unselected patients (32%). Unilateral FTP was significantly more frequent on the right than on the left side in both groups (15% right vs. 8% left). The presence of FTP ipsilateral to stroke side was not associated with involvement of the PCA territory versus no FTP on the stroke side.
CONCLUSIONS
CONCLUSIONS
FTP is present in approximately 30% of ischemic stroke patients and unselected hospital populations and was detected significantly more frequently on the right versus left side in both groups. PCA territory infarction was not associated with the presence of ipsilateral FTP.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
297-304Subventions
Organisme : The Swedish Research Council
ID : 2019-01757
Organisme : NINDS NIH HHS
ID : R01NS082285
Pays : United States
Organisme : NINDS NIH HHS
ID : R01NS086905
Pays : United States
Organisme : NINDS NIH HHS
ID : R01NS0869051
Pays : United States
Organisme : NINDS NIH HHS
ID : U19NS115388
Pays : United States
Organisme : The Swedish Stroke Association
ID : I-ALF 47447
Organisme : The Swedish Stroke Association
ID : YF-ALF 43435
Organisme : Crafoordska Stiftelsen
ID : 20180610
Organisme : NIA NIH HHS
ID : U19NS115388
Pays : United States
Organisme : The Swedish Foundation for International Cooperation in Research and Higher Education
ID : IB2018-7532
Organisme : National Institute of Neurological Disorders and Stroke
ID : R01NS082285
Organisme : National Institute of Neurological Disorders and Stroke
ID : R01NS086905
Organisme : National Institute of Neurological Disorders and Stroke
ID : R01NS0869051
Organisme : National Institute of Neurological Disorders and Stroke
ID : U19NS115388
Organisme : National Institute on Aging
ID : U19NS115388
Informations de copyright
© 2021 The Authors. Acta Neurologica Scandinavica published by John Wiley & Sons Ltd.
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