Subphthalocyanines as Efficient Photosensitizers with Nanomolar Photodynamic Activity against Cancer Cells.
Journal
Journal of medicinal chemistry
ISSN: 1520-4804
Titre abrégé: J Med Chem
Pays: United States
ID NLM: 9716531
Informations de publication
Date de publication:
09 12 2021
09 12 2021
Historique:
pubmed:
24
11
2021
medline:
22
1
2022
entrez:
23
11
2021
Statut:
ppublish
Résumé
Because cancer is the second leading cause of death globally, investigation of new photosensitizers for photodynamic therapy is highly desirable. In this work, different peripherally substituted subphthalocyanines (SubPcs) with either a benzocrown moiety (CE-) or a tyrosine methyl ester (Tyr-) as the axial ligand have been prepared. Target SubPcs showed high Φ
Identifiants
pubmed: 34813305
doi: 10.1021/acs.jmedchem.1c01584
doi:
Substances chimiques
Isoindoles
0
Photosensitizing Agents
0
phthalocyanine
V5PUF4VLGY
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM