rSjP40 Inhibited the Activity of Collagen Type I Promoter
ETS-1
collagen type I alpha I
hepatic stellate cells
liver fibrosis
schistosoma japonicum protein P40
Journal
Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250
Informations de publication
Date de publication:
2021
2021
Historique:
received:
27
08
2021
accepted:
22
10
2021
entrez:
25
11
2021
pubmed:
26
11
2021
medline:
26
11
2021
Statut:
epublish
Résumé
Liver fibrosis is a severe disease characterized by excessive deposition of extracellular matrix (ECM) components in the liver. Activated hepatic stellate cells (HSCs) are a major source of ECM and a key regulator of liver fibrosis. Collagen type I alpha I (COL1A1) is one of the main components of ECM and is a major component in fibrotic tissues. Previously, we demonstrated that soluble egg antigen from
Identifiants
pubmed: 34820381
doi: 10.3389/fcell.2021.765616
pii: 765616
pmc: PMC8606555
doi:
Types de publication
Journal Article
Langues
eng
Pagination
765616Informations de copyright
Copyright © 2021 Li, Zhang, Zhang, Chen, Chen, Zhu, Chen, Duan and Duan.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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