The anticancer and free radical scavenging potential of the Unani medicine
Agaricus albus
Ghariqoon
MCF-7
Unani
anti-cancer
antioxidant
cancer cell line
Journal
Hormone molecular biology and clinical investigation
ISSN: 1868-1891
Titre abrégé: Horm Mol Biol Clin Investig
Pays: Germany
ID NLM: 101538885
Informations de publication
Date de publication:
24 Nov 2021
24 Nov 2021
Historique:
received:
08
07
2021
accepted:
10
11
2021
pubmed:
26
11
2021
medline:
24
11
2022
entrez:
25
11
2021
Statut:
epublish
Résumé
Traditional Unani medicine plays a major role in maintaining health in developing countries. For ages, Unani physicians have described many Classical Unani Formulations (CUF) for their anti-cancerous action ( Cytotoxic effect was assessed using MTT assay kit and free radical scavenging activity was done by using DPPH assay. Aqueous, hydro-ethanol and methanolic extracts were used at different concentrations. All extracts were shown good antioxidant and cytotoxic activity. Among all extracts, maximum cytotoxic effect was observed in methanolic extract and aqueous extract at the concentration of 1,000 μg against MCF-7 cell line in comparison to paclitaxel. The maximum antioxidant activity was observed in the hydroethanolic extract at the concentration of 1,000 μg against the MCF-7 cell line in comparison to ascorbic acid. The present study advocates, the anticancer and antioxidant property of
Identifiants
pubmed: 34821112
pii: hmbci-2021-0057
doi: 10.1515/hmbci-2021-0057
doi:
Substances chimiques
Antioxidants
0
Free Radicals
0
Plant Extracts
0
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
219-223Informations de copyright
© 2021 Walter de Gruyter GmbH, Berlin/Boston.
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