Reduction in cerebral oxygen metabolism in subcortical regions may be a biomarker of cognitive decline in people living with human immunodeficiency virus.
HAND
HIV
antiretroviral therapy
cerebral blood flow
cerebral oxygen metabolism
Journal
European journal of neurology
ISSN: 1468-1331
Titre abrégé: Eur J Neurol
Pays: England
ID NLM: 9506311
Informations de publication
Date de publication:
04 2022
04 2022
Historique:
received:
25
09
2021
accepted:
16
11
2021
pubmed:
26
11
2021
medline:
5
4
2022
entrez:
25
11
2021
Statut:
ppublish
Résumé
Regional cerebral blood flow (rCBF) and oxygen metabolism (rCMRO Treatment-naïve PLHIV underwent neurocognitive assessment and magnetic resonance (MR) measurement of rCBF and rCMRO Thirty PLHIV completed baseline and 12-month assessments (29 with rCMRO In recently diagnosed PLHIV, no association was found between rCBF or rCMRO
Sections du résumé
BACKGROUND AND PURPOSE
Regional cerebral blood flow (rCBF) and oxygen metabolism (rCMRO
METHODS
Treatment-naïve PLHIV underwent neurocognitive assessment and magnetic resonance (MR) measurement of rCBF and rCMRO
RESULTS
Thirty PLHIV completed baseline and 12-month assessments (29 with rCMRO
CONCLUSIONS
In recently diagnosed PLHIV, no association was found between rCBF or rCMRO
Substances chimiques
Biomarkers
0
Oxygen
S88TT14065
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
1062-1074Subventions
Organisme : NINDS NIH HHS
ID : R01 NS062754
Pays : United States
Informations de copyright
© 2021 European Academy of Neurology.
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