Novel Histomorphometrical Approach to Evaluate the Integration Pattern and Functionality of Barrier Membranes.

barrier membranes biomaterial integration cellular immigration collagen guided bone regeneration (GBR) histomorphometrical analysis hyaluronic acid

Journal

Dentistry journal
ISSN: 2304-6767
Titre abrégé: Dent J (Basel)
Pays: Switzerland
ID NLM: 101716125

Informations de publication

Date de publication:
25 Oct 2021
Historique:
received: 24 09 2021
revised: 19 10 2021
accepted: 21 10 2021
entrez: 25 11 2021
pubmed: 26 11 2021
medline: 26 11 2021
Statut: epublish

Résumé

GBR (guided bone regeneration) is a standard procedure for building up bony defects in the jaw. In this procedure, resorbable membranes made of bovine and porcine collagen are increasingly being used, which, in addition to many possible advantages, could have the potential disadvantage of a shorter barrier functionality, especially when augmenting large-volume defects. Thus, it is of importance to evaluate the integration behavior and especially the standing time of barrier membranes using specialized methods to predict its respective biocompatibility. This study is intended to establish a new histomorphometrical analysis method to quantify the integration rate of collagen-based barrier membranes. Three commercially available barrier membranes, i.e., non-crosslinked membranes (BioGide

Identifiants

pubmed: 34821591
pii: dj9110127
doi: 10.3390/dj9110127
pmc: PMC8618445
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Nicola Ottenbacher (N)

Clinical Division of Oral Surgery, Dental University Clinic, Medical University of Vienna, 1090 Vienna, Austria.

Said Alkildani (S)

BerlinAnalytix GmbH, 12109 Berlin, Germany.

Tadas Korzinskas (T)

BerlinAnalytix GmbH, 12109 Berlin, Germany.

Jens Pissarek (J)

Biotrics Bioimplants AG, 12109 Berlin, Germany.

Christian Ulm (C)

Clinical Division of Oral Surgery, Dental University Clinic, Medical University of Vienna, 1090 Vienna, Austria.

Ole Jung (O)

Clinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, 18057 Rostock, Germany.

Bernd Sundag (B)

Clinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, 18057 Rostock, Germany.

Olaf Bellmann (O)

Research Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.

Sanja Stojanovic (S)

Scientific Research Center for Biomedicine, Department for Cell and Tissue Engineering, Faculty of Medicine, University of of Niš, 18000 Niš, Serbia.
Department of Biology and Human Genetics, Faculty of Medicine, University of Niš, 18000 Niš, Serbia.

Stevo Najman (S)

Scientific Research Center for Biomedicine, Department for Cell and Tissue Engineering, Faculty of Medicine, University of of Niš, 18000 Niš, Serbia.
Department of Biology and Human Genetics, Faculty of Medicine, University of Niš, 18000 Niš, Serbia.

Werner Zechner (W)

Clinical Division of Oral Surgery, Dental University Clinic, Medical University of Vienna, 1090 Vienna, Austria.
Austrian Cluster for Tissue Regeneration, 1200 Vienna, Austria.

Mike Barbeck (M)

Department of Ceramic Materials, Chair of Advanced Ceramic Materials, Institute for Materials Science and Technologies, Technical University Berlin, 10623 Berlin, Germany.

Classifications MeSH