Real-World Outcomes of Glucose Sensor Use in Type 1 Diabetes-Findings from a Large UK Centre.


Journal

Biosensors
ISSN: 2079-6374
Titre abrégé: Biosensors (Basel)
Pays: Switzerland
ID NLM: 101609191

Informations de publication

Date de publication:
15 Nov 2021
Historique:
received: 18 10 2021
revised: 07 11 2021
accepted: 10 11 2021
entrez: 25 11 2021
pubmed: 26 11 2021
medline: 28 1 2022
Statut: epublish

Résumé

Flash glucose monitoring (FGM) and real-time continuous glucose monitoring (RT-CGM) are increasingly used in clinical practice, with improvements in HbA1c and time in range (TIR) reported in clinical studies. We aimed to evaluate the impact of FGM and RT-CGM use on glycaemic outcomes in adults with type 1 diabetes (T1DM) under routine clinical care. We performed a retrospective data analysis from electronic outpatient records and proprietary web-based glucose monitoring platforms. We measured HbA1c (pre-sensor vs. on-sensor data) and sensor-based outcomes from the previous three months as per the international consensus on RT-CGM reporting guidelines. Amongst the 789 adults with T1DM, HbA1c level decreased from 61.0 (54.0, 71.0) mmol/mol to 57 (49, 65.8) mmol/mol in 561 people using FGM, and from 60.0 (50.0, 70.0) mmol/mol to 58.8 (50.3, 66.8) mmol/mol in 198 using RT-CGM (

Identifiants

pubmed: 34821673
pii: bios11110457
doi: 10.3390/bios11110457
pmc: PMC8615559
pii:
doi:

Substances chimiques

Blood Glucose 0
Glycated Hemoglobin A 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Références

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Auteurs

Kyuhan Lee (K)

Medical School, University of Manchester, Manchester M13 9PL, UK.

Shakthi Gunasinghe (S)

Medical School, University of Manchester, Manchester M13 9PL, UK.

Alyson Chapman (A)

Manchester Academic Health Science Centre, Diabetes, Endocrinology & Metabolism Centre, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.

Lynne A Findlow (LA)

Manchester Academic Health Science Centre, Diabetes, Endocrinology & Metabolism Centre, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.

Jody Hyland (J)

Manchester Academic Health Science Centre, Diabetes, Endocrinology & Metabolism Centre, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.

Sheetal Ohol (S)

Manchester Academic Health Science Centre, Diabetes, Endocrinology & Metabolism Centre, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.

Andrea Urwin (A)

Manchester Academic Health Science Centre, Diabetes, Endocrinology & Metabolism Centre, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.

Martin K Rutter (MK)

Manchester Academic Health Science Centre, Diabetes, Endocrinology & Metabolism Centre, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.
Division of Diabetes, Endocrinology & Gastroenterology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.

Jonathan Schofield (J)

Manchester Academic Health Science Centre, Diabetes, Endocrinology & Metabolism Centre, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.
Division of Diabetes, Endocrinology & Gastroenterology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.

Hood Thabit (H)

Manchester Academic Health Science Centre, Diabetes, Endocrinology & Metabolism Centre, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.
Division of Diabetes, Endocrinology & Gastroenterology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.

Lalantha Leelarathna (L)

Manchester Academic Health Science Centre, Diabetes, Endocrinology & Metabolism Centre, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK.
Division of Diabetes, Endocrinology & Gastroenterology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.

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Classifications MeSH