Natural Products Induce Lysosomal Membrane Permeabilization as an Anticancer Strategy.
apoptosis
cancer
lysosomal membrane permeabilization
lysosomes
Journal
Medicines (Basel, Switzerland)
ISSN: 2305-6320
Titre abrégé: Medicines (Basel)
Pays: Switzerland
ID NLM: 101671069
Informations de publication
Date de publication:
10 Nov 2021
10 Nov 2021
Historique:
received:
31
08
2021
revised:
03
11
2021
accepted:
08
11
2021
entrez:
25
11
2021
pubmed:
26
11
2021
medline:
26
11
2021
Statut:
epublish
Résumé
Cancer is a global health and economic issue. The majority of anticancer therapies become ineffective due to frequent genomic turnover and chemoresistance. Furthermore, chemotherapy and radiation are non-specific, killing all rapidly dividing cells including healthy cells. In this review, we examine the ability of some natural products to induce lysosomal-mediated cell death in neoplastic cells as a way to kill them more specifically than conventional therapies. This list is by no means exhaustive. We postulate mechanisms to explain lysosomal membrane permeabilization and its role in triggering cell death in cancer cells.
Identifiants
pubmed: 34822366
pii: medicines8110069
doi: 10.3390/medicines8110069
pmc: PMC8624533
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Cancer Lett. 2014 Jun 28;348(1-2):156-66
pubmed: 24662747
Biochim Biophys Acta. 2014 Jan;1841(1):190-203
pubmed: 24120917
Cell Death Differ. 2002 Sep;9(9):934-44
pubmed: 12181744
JACS Au. 2021 Jul 08;1(8):1240-1256
pubmed: 34467362
Biochem J. 2001 Jun 1;356(Pt 2):549-55
pubmed: 11368784
Biochem J. 2001 Oct 15;359(Pt 2):335-43
pubmed: 11583579
Pharmacol Res. 2009 Jun;59(6):365-78
pubmed: 19429468
Cell Biol Toxicol. 2016 Oct;32(5):451-64
pubmed: 27400986
Oncotarget. 2015 Jul 10;6(19):17328-41
pubmed: 26093146
Redox Biol. 2018 Sep;18:65-76
pubmed: 29986210
Cell Death Dis. 2015 Jan 29;6:e1624
pubmed: 25633293
Cancer Lett. 2013 Feb 28;329(2):207-16
pubmed: 23200666
Leuk Res. 2000 Sep;24(9):769-74
pubmed: 10978781
Trends Pharmacol Sci. 2008 Jan;29(1):22-8
pubmed: 18037508
J Clin Oncol. 1999 Sep;17(9):2941-53
pubmed: 10561374
Biomedicines. 2019 Jul 19;7(3):
pubmed: 31330969
Biol Chem. 2002 Jul-Aug;383(7-8):1035-44
pubmed: 12437086
J Cell Biochem. 2019 Jun;120(6):9608-9623
pubmed: 30525230
Oxid Med Cell Longev. 2017;2017:3749157
pubmed: 28757908
Sci Rep. 2021 May 19;11(1):10609
pubmed: 34011952
Oncogene. 2008 Oct 27;27(50):6434-51
pubmed: 18955971
Cell Death Dis. 2012 Apr 05;3:e293
pubmed: 22476101
Biomed Pharmacother. 2020 Jan;121:109594
pubmed: 31707344
Science. 2013 Aug 2;341(6145):569-73
pubmed: 23828891
Curr Pharm Biotechnol. 2012 Jun;13(8):1426-38
pubmed: 22423614
J Hepatol. 2019 Oct;71(4):763-772
pubmed: 31220470
Cancer Sci. 2021 Aug;112(8):3324-3337
pubmed: 34051014
Cell Death Dis. 2013 Feb 21;4:e507
pubmed: 23429293
Cancer Res. 2007 Mar 1;67(5):2217-25
pubmed: 17332352
Photochem Photobiol. 2012 Mar-Apr;88(2):461-8
pubmed: 22220628
PLoS One. 2012;7(10):e46749
pubmed: 23056433
J Biomed Sci. 2011 Jan 06;18:1
pubmed: 21208456
Cell Death Differ. 2012 Sep;19(9):1482-94
pubmed: 22421964
Curr Med Chem. 2020;27(24):4087-4108
pubmed: 29848266
FEBS Lett. 2000 Mar 17;470(1):35-9
pubmed: 10722841
Cancer Lett. 2015 Sep 28;366(1):19-31
pubmed: 26118776
J Cell Mol Med. 2019 Mar;23(3):1798-1812
pubmed: 30565390
Oncotarget. 2015 Jan 20;6(2):1143-56
pubmed: 25544758
Essays Biochem. 2010;47:99-114
pubmed: 20533903
PLoS One. 2013 Apr 25;8(4):e62839
pubmed: 23638153
Biochim Biophys Acta. 2009 Apr;1793(4):746-54
pubmed: 18948147
J Exp Med. 2004 Aug 16;200(4):425-35
pubmed: 15314073
Cancer Lett. 2013 May 28;332(2):265-74
pubmed: 20598437
J Biol Chem. 2016 Oct 28;291(44):22936-22948
pubmed: 27587392
Autophagy. 2008 May;4(4):487-99
pubmed: 18305408
Exp Cell Res. 2012 Jul 1;318(11):1245-51
pubmed: 22465226
Mol Cell. 2011 Aug 5;43(3):449-63
pubmed: 21737330
Eur J Cancer Prev. 2013 Nov;22(6):577-84
pubmed: 23603746
Biomed Res Int. 2014;2014:150845
pubmed: 25013758
Mol Cancer Ther. 2018 Oct;17(10):2079-2090
pubmed: 30030299
Biochem Pharmacol. 2018 Apr;150:267-279
pubmed: 29476714
Chembiochem. 2021 Jul 15;:
pubmed: 34263972
IUBMB Life. 2006 Sep;58(9):531-9
pubmed: 17002981
Sci Rep. 2018 Jan 31;8(1):1952
pubmed: 29386662
Int J Womens Health. 2013 Sep 05;5:557-69
pubmed: 24043955
Nature. 2015 Aug 20;524(7565):361-5
pubmed: 26168401
Cell Death Dis. 2020 Aug 26;11(8):708
pubmed: 32848130
PLoS One. 2019 Aug 14;14(8):e0216024
pubmed: 31412041
Nat Cell Biol. 2005 Sep;7(9):847-9
pubmed: 16136179
Biochem J. 2021 Jun 25;478(12):2233-2245
pubmed: 34037204
Mol Carcinog. 2017 Feb;56(2):337-348
pubmed: 27149078
J Clin Invest. 2013 Jan;123(1):315-28
pubmed: 23202731
Neoplasia. 2003 Nov-Dec;5(6):533-45
pubmed: 14965446
Mol Cell Biol. 2003 Jan;23(2):665-76
pubmed: 12509464
J Exp Med. 2003 May 19;197(10):1323-34
pubmed: 12756268
Org Lett. 2010 Oct 1;12(19):4292-5
pubmed: 20804151
Biochim Biophys Acta. 2016 Nov;1860(11 Pt A):2363-2376
pubmed: 27418237
J Biol Chem. 1998 Apr 17;273(16):9357-60
pubmed: 9545256
J Biol Chem. 2008 Jul 4;283(27):19140-50
pubmed: 18469004