Determinants of asthma in Ethiopia: age and sex matched case control study with special reference to household fuel exposure and housing characteristics.
Asthma
Biomass fuel
Ethiopia
Household fuel exposure
Housing characteristic
Matched case control
Journal
Asthma research and practice
ISSN: 2054-7064
Titre abrégé: Asthma Res Pract
Pays: England
ID NLM: 101670236
Informations de publication
Date de publication:
25 Nov 2021
25 Nov 2021
Historique:
received:
02
08
2021
accepted:
14
11
2021
entrez:
26
11
2021
pubmed:
27
11
2021
medline:
27
11
2021
Statut:
epublish
Résumé
Asthma is a chronic inflammatory disorder characterized by airway obstruction and hyper-responsiveness. Studies suggest that household fuel exposure and housing characteristics are associated with air way related allergy. But there remains to be a considerable uncertainty about whether that reflects an association with asthma. This study endeavored to bridge the gap by identifying factors associated with asthma, with special reference to household fuel exposure and housing characteristics in selected public hospitals in Addis Ababa, Ethiopia. We conducted a hospital-based matched case-control study. A total of 483 study participants were selected from two Ethiopian referral hospitals using a sequential sampling technique, with 161 cases and 322 controls. Standard questionnaire from the European Community Respiratory Health Survey II (ECRHS II) and the American Thoracic Society Division of Lung Disease (ATS-DLD-78) were used to collect household related data. Conditional logistic regression model was applied to identify the determinants of asthma. Both crude and adjusted odds ratios with 95% confidence interval (CI) were used to identify predictors of asthma. The response rate for both cases and controls was 99.17%. The odds of developing asthma was about four times higher among those who used agricultural residues for cooking (AOR: 3.81, 95% CI: 1.05, 13.79)., about five times higher among those who used wood for cooking (AOR: 4.95, 95% CI: 2.1, 11.69), nearly five times higher among those who had family history of asthma (AOR: 4.72, 95% CI: 1.54, 14.45), just over six times higher among those who smoke tobacco (AOR: 6.16, 95% CI: 1.31, 29.09) and over ten times higher among those who do not practice door opening, while cooking (AOR: 10.25, 95% CI: 3.97, 26.49). Family history of asthma, tobacco smoking, use of solid fuels including, woods and agricultural residues were associated with development of asthma. To reduce the risk of asthma, people should practice door opening, while cooking, and must avoid using wood and agricultural residues for cooking and should also refrain from tobacco smoking.
Sections du résumé
BACKGROUND
BACKGROUND
Asthma is a chronic inflammatory disorder characterized by airway obstruction and hyper-responsiveness. Studies suggest that household fuel exposure and housing characteristics are associated with air way related allergy. But there remains to be a considerable uncertainty about whether that reflects an association with asthma. This study endeavored to bridge the gap by identifying factors associated with asthma, with special reference to household fuel exposure and housing characteristics in selected public hospitals in Addis Ababa, Ethiopia.
METHODS
METHODS
We conducted a hospital-based matched case-control study. A total of 483 study participants were selected from two Ethiopian referral hospitals using a sequential sampling technique, with 161 cases and 322 controls. Standard questionnaire from the European Community Respiratory Health Survey II (ECRHS II) and the American Thoracic Society Division of Lung Disease (ATS-DLD-78) were used to collect household related data. Conditional logistic regression model was applied to identify the determinants of asthma. Both crude and adjusted odds ratios with 95% confidence interval (CI) were used to identify predictors of asthma.
RESULTS
RESULTS
The response rate for both cases and controls was 99.17%. The odds of developing asthma was about four times higher among those who used agricultural residues for cooking (AOR: 3.81, 95% CI: 1.05, 13.79)., about five times higher among those who used wood for cooking (AOR: 4.95, 95% CI: 2.1, 11.69), nearly five times higher among those who had family history of asthma (AOR: 4.72, 95% CI: 1.54, 14.45), just over six times higher among those who smoke tobacco (AOR: 6.16, 95% CI: 1.31, 29.09) and over ten times higher among those who do not practice door opening, while cooking (AOR: 10.25, 95% CI: 3.97, 26.49).
CONCLUSION
CONCLUSIONS
Family history of asthma, tobacco smoking, use of solid fuels including, woods and agricultural residues were associated with development of asthma. To reduce the risk of asthma, people should practice door opening, while cooking, and must avoid using wood and agricultural residues for cooking and should also refrain from tobacco smoking.
Identifiants
pubmed: 34823608
doi: 10.1186/s40733-021-00080-2
pii: 10.1186/s40733-021-00080-2
pmc: PMC8613982
doi:
Types de publication
Journal Article
Langues
eng
Pagination
14Informations de copyright
© 2021. The Author(s).
Références
Am J Prev Med. 2014 Dec;47(6):796-802
pubmed: 25245799
Aust N Z J Public Health. 2001;25(1):44-9
pubmed: 11297301
J Epidemiol Community Health. 2004 Jun;58(6):476-80
pubmed: 15143115
J Asthma. 2017 May;54(4):347-356
pubmed: 27589676
J Urban Health. 2013 Feb;90(1):116-29
pubmed: 22689297
Clin Chest Med. 2012 Dec;33(4):649-65
pubmed: 23153607
BMC Pulm Med. 2017 Jan 5;17(1):3
pubmed: 28056916
Environ Health Perspect. 2003 Jan;111(1):71-8
pubmed: 12515681
BMJ. 2011 May 17;342:d3062
pubmed: 21586474
Int J Epidemiol. 2018 Aug 1;47(4):1106-1117
pubmed: 29534228
Environ Health Prev Med. 2003 Mar;8(1):13-7
pubmed: 21432110
Asian Pac J Allergy Immunol. 2008 Dec;26(4):213-22
pubmed: 19317340
Elife. 2019 Nov 15;8:
pubmed: 31729315
Afr Health Sci. 2014 Sep;14(3):707-15
pubmed: 25352892
Thorax. 2016 Feb;71(2):154-60
pubmed: 26699762
J Expo Anal Environ Epidemiol. 2004;14 Suppl 1:S110-7
pubmed: 15118752
Prim Care Respir J. 2011 Sep;20(3):240-8
pubmed: 21509418
Environ Health. 2014 Mar 24;13(1):21
pubmed: 24655424
J Epidemiol. 2014;24(3):230-8
pubmed: 24747197
Eur Respir J. 2002 Nov;20(5):1071-9
pubmed: 12449157
Thorax. 2011 Dec;66(12):1051-7
pubmed: 21730351
Indian J Med Res. 2004 Nov;120(5):443-53
pubmed: 15591628
BMC Res Notes. 2019 Sep 23;12(1):608
pubmed: 31547859
Arch Pediatr Adolesc Med. 2005 Feb;159(2):151-7
pubmed: 15699309
Asian Pac J Allergy Immunol. 2015 Jun;33(2):152-60
pubmed: 26141037
Thorax. 1995 Jan;50(1):74-8
pubmed: 7886654
Indoor Air. 2007 Aug;17(4):297-304
pubmed: 17661926
Sci Total Environ. 2018 Mar;616-617:1513-1523
pubmed: 29107378
Indoor Air. 2016 Apr;26(2):179-92
pubmed: 25833176
Bull World Health Organ. 1985;63(1):11-26
pubmed: 3872729
Thorax. 2002 Dec;57(12):1034-9
pubmed: 12454297
Clin Exp Allergy. 2015 Jan;45(1):200-10
pubmed: 25077415
Ann Trop Paediatr. 1994;14(1):15-9
pubmed: 7516128
Allergy Asthma Proc. 2015 Jul-Aug;36(4):256-61
pubmed: 26108082
Burns. 2012 Sep;38(6):790-5
pubmed: 22652477
Respir Med. 2013 Dec;107(12):1845-51
pubmed: 24094943
Indoor Air. 2017 Mar;27(2):478-486
pubmed: 27317363