Evaluating the Clinical Risk Factors Associated With Miscarriages in Women in Karachi, Pakistan.

miscarriages pakistan pregnancy loss risk analysis risk factors

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
Oct 2021
Historique:
accepted: 21 10 2021
entrez: 26 11 2021
pubmed: 27 11 2021
medline: 27 11 2021
Statut: epublish

Résumé

Introduction Spontaneous pregnancy loss is unquestionably common worldwide, with roughly 5% of pregnancies ending in this way. Miscarriage can lead to serious psychological issues for women as well as their mothers. Although, it is irreversible but can be prevented through proper risk assessment of women. The goal of this study is to find clinical predictors of miscarriages in Karachi, Pakistani women. Methodology The study is a retrospective chart review that used data of women having livebirth and miscarriages at the Liaquat National Hospital Karachi Pakistan. Data of a total of 517 women were included in the study, out of which 453 have had a live birth, and 64 had miscarriages. To determine the factors associated with miscarriages, multivariable logistic regression was used.  Results The mean age of women was 31.08 (±5.10) years. Age of mother over 40 years (adjusted odds ratio [AOR]=10.28; p-value=0.001), overweight and obesity (AOR=3.01; p-value=0.001) and history of miscarriage (AOR=2.91; p-value=0.003) are variables significantly associated with miscarriages. Conclusion Findings of the current study shown that risk factors of miscarriages included age of mother, increased BMI and previous history of miscarriages. All these factors need to be considered while providing antenatal care to mothers to mitigate the risk of miscarriages.

Identifiants

pubmed: 34824942
doi: 10.7759/cureus.19057
pmc: PMC8610211
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e19057

Informations de copyright

Copyright © 2021, Iqbal et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Références

Hum Reprod. 2012 Jul;27(7):1882-6
pubmed: 22552692
Acta Obstet Gynecol Scand. 2005 Dec;84(12):1197-201
pubmed: 16305708
Pituitary. 2001 Jan-Apr;4(1-2):93-9
pubmed: 11824514
Eur J Obstet Gynecol Reprod Biol. 2016 Nov;206:57-63
pubmed: 27639132
BJOG. 2010 Sep;117(10):1211-9
pubmed: 20618319
N Engl J Med. 1988 Dec 22;319(25):1617-23
pubmed: 3200277
Am J Epidemiol. 2007 Jun 15;165(12):1380-8
pubmed: 17351291
Reprod Biomed Online. 2008 Jul;17(1):101-13
pubmed: 18616898
Best Pract Res Clin Obstet Gynaecol. 2007 Apr;21(2):229-47
pubmed: 17317322
Med Princ Pract. 2015;24 Suppl 1:38-55
pubmed: 25428171
Hum Reprod Update. 2002 Mar-Apr;8(2):141-54
pubmed: 12099629
Reprod Biomed Online. 2007 Mar;14(3):314-21
pubmed: 17359584
Hum Reprod. 2002 Dec;17(12):3220-3
pubmed: 12456627
PLoS One. 2013 Sep 30;8(9):e75759
pubmed: 24098721

Auteurs

Zafar Iqbal (Z)

Emergency Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Emergency Department, The Kidney Center, Karachi, PAK.

Syed Daniyal A Jilanee (SDA)

Medical College, Liaquat National Hospital and Medical College, Karachi, PAK.

Lalitha P Uppada (LP)

Medical College, Gandhi Medical College, Hyderabad, IND.

Samahir Imtiaz (S)

Medical College, Liaquat National Hospital and Medical College, Karachi, PAK.

Hamadullah Khan (H)

Medical School, Ziauddin University, Karachi, PAK.

Syed Muhammad Huzaifa Shah (SMH)

Medical Education, Ziauddin University, Karachi, PAK.

Sohaib Tousif (S)

Medical School, Ziauddin Medical University, Karachi, PAK.

Anum Rahim (A)

Indus Hospital Research Center, The Indus Hospital, Karachi, PAK.

Classifications MeSH