An unusual detection of 2-amino-3-(2-chlorobenzoyl)-5-ethylthiophene and 2-methylamino-5-chlorobenzophenone in illicit yellow etizolam tablets marked "5617" seized in the Republic of Ireland.
2-amino-3-(2-chlorobenzoyl)-5-ethylthiophene
2-methylamino-5-chlorobenzophenone
5617
etizolam
Journal
Drug testing and analysis
ISSN: 1942-7611
Titre abrégé: Drug Test Anal
Pays: England
ID NLM: 101483449
Informations de publication
Date de publication:
Mar 2022
Mar 2022
Historique:
revised:
18
10
2021
received:
05
10
2021
accepted:
18
10
2021
pubmed:
27
11
2021
medline:
5
4
2022
entrez:
26
11
2021
Statut:
ppublish
Résumé
Benzodiazepines are a class of compounds used clinically to treat a variety of conditions including anxiety and insomnia. Their potential for abuse has led to a surge in their availability on the illegal drugs market. End users often rely on markings on illicit tablets to identify their contents. However, falsified tablets mimicking genuine pharmaceutical preparations often contain ingredients that differ from what people believe they are taking. The absence of any quality control of the content, purity, or strength of fake tablets can result in adverse effects or even fatal outcomes. In recent years, drug seizures involving illicit round yellow tablets marked "5" on one side and "5617" below a scoreline on the reverse have been submitted to Forensic Science Ireland (FSI) by An Garda Síochána (Irish Police) from throughout the Republic of Ireland. These findings relate to 26 different seizures; the cumulative tablet total seized was in excess of 20,000, and the total number of tablets of this description analyzed at FSI was 141. Irish users assume that the active ingredient present was diazepam. The qualitative analytical results for these tablets are reported. All tablets were found to contain 2-methylamino-5-chlorobenzophenone. In addition, the tablets contained either 2-amino-3-(2-chlorobenzoyl)-5-ethylthiophene or etizolam or both. The constituents were present in varying relative amounts in visually similar tablets. Neither 2-amino-5-chlorobenzophenone nor 2-amino-3-(2-chlorobenzoyl)-5-ethylthiophene had previously been found in tablets analyzed at FSI.
Substances chimiques
Benzophenones
0
Tablets
0
2-methylamino-5-chlorobenzophenone
1022-13-5
etizolam
A76XI0HL37
Diazepam
Q3JTX2Q7TU
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
531-538Informations de copyright
© 2021 John Wiley & Sons, Ltd.
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