Molecular Detection of
Lyme borreliosis
Lyme neuroborreliosis
cerebrospinal fluid
clinical diagnostic
optimization
polymerase chain reaction (PCR)
Journal
Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402
Informations de publication
Date de publication:
12 Nov 2021
12 Nov 2021
Historique:
received:
08
10
2021
revised:
02
11
2021
accepted:
08
11
2021
entrez:
27
11
2021
pubmed:
28
11
2021
medline:
28
11
2021
Statut:
epublish
Résumé
The main tools for clinical diagnostics of Lyme neuroborreliosis (LNB) are based on serology, i.e., detection of antibodies in cerebrospinal fluid (CSF). In some cases, PCR may be used as a supplement, e.g., on CSF from patients with early LNB. Standardisation of the molecular methods and systematic evaluation of the pre-analytical handling is lacking. To increase the analytical sensitivity for detection of
Identifiants
pubmed: 34829435
pii: diagnostics11112088
doi: 10.3390/diagnostics11112088
pmc: PMC8623531
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : The European Union through the European Regional Development Fund and the Interreg NorthSea Region Programme 2014-2020 as part of the NorthTick project
ID : J-No: 38-2-7-19
Organisme : Futurum Academy for Healthcare, Region Jönkoping County, Division of Medical Diagnostics, Region of Jönköping County
ID : https://plus.rjl.se/futurum
Organisme : Interreg IV A Program ScandTick
ID : 167226
Organisme : Interreg V program ScandTick Innovation
ID : 2015-000167
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