Suppression of Electrographic Seizures Is Associated with Amelioration of QTc Interval Prolongation in Patients with Traumatic Brain Injury.
QTc interval
brain–heart interaction
seizure
spatial QTS-T angle
traumatic brain injury
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
18 Nov 2021
18 Nov 2021
Historique:
received:
22
06
2021
revised:
01
11
2021
accepted:
16
11
2021
entrez:
27
11
2021
pubmed:
28
11
2021
medline:
28
11
2021
Statut:
epublish
Résumé
Disorders in electroencephalography (EEG) are commonly noted in patients with traumatic brain injury (TBI) and may be associated with electrocardiographic disturbances. Electrographic seizures (ESz) are the most common features in these patients. This study aimed to explore the relationship between ESz and possible changes in QTc interval and spatial QRS-T angle both during ESz and after ESz resolution. Adult patients with TBI were studied. Surface 12-lead ECGs were recorded using a Cardiax device during ESz events and 15 min after their effective suppression using barbiturate infusion. The ESz events were diagnosed using Masimo Root or bispectral index (BIS) devices. Of the 348 patients considered for possible inclusion, ESz were noted in 72, with ECG being recorded in 21. Prolonged QTc was noted during ESz but significantly ameliorated after ESz suppression (540.19 ± 60.68 ms vs. 478.67 ± 38.52 ms, QTc interval prolongation occurs during ESz events in TBI patients but both it and regional cerebral oximetry are improved after suppression of seizures.
Identifiants
pubmed: 34830656
pii: jcm10225374
doi: 10.3390/jcm10225374
pmc: PMC8622115
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
J Neurosci. 2016 Aug 24;36(34):8777-9
pubmed: 27559160
J Electrocardiol. 2018 May - Jun;51(3):499-507
pubmed: 29310923
J Electrocardiol. 2018 Mar - Apr;51(2):170-174
pubmed: 29174097
Pediatr Crit Care Med. 2010 Jul;11(4):514-22
pubmed: 19935441
Neuroimage. 2019 Mar;188:403-410
pubmed: 30572111
Br J Anaesth. 2014 May;112(5):803-15
pubmed: 24638232
Scand J Trauma Resusc Emerg Med. 2017 Aug 25;25(1):85
pubmed: 28841884
Curr Clin Pharmacol. 2017;12(4):210-222
pubmed: 29473523
Appl Netw Sci. 2017;2(1):29
pubmed: 30443583
A A Pract. 2019 Oct 1;13(7):281-283
pubmed: 31385818
Circ Res. 2017 Aug 4;121(4):451-468
pubmed: 28775014
Neurobiol Dis. 2019 Mar;123:115-121
pubmed: 29859872
Cereb Cortex. 2020 Mar 21;30(2):439-450
pubmed: 31163086
J Neurosurg Anesthesiol. 2021 Jul 1;33(3):258-262
pubmed: 31633577
Neurosurg Clin N Am. 2016 Oct;27(4):499-508
pubmed: 27637399
Epilepsia. 2013 Mar;54(3):518-22
pubmed: 23157562
Int J Cardiol. 2017 Apr 1;232:243-246
pubmed: 28100427
J Clin Neurophysiol. 2013 Aug;30(4):371-5
pubmed: 23912575
J Neurosurg Anesthesiol. 2021 Oct 1;33(4):285-292
pubmed: 32011413
Epilepsia. 2010 Jan;51(1):170-3
pubmed: 19490047
Epilepsia. 2010 Feb;51(2):221-32
pubmed: 19732135
Seizure. 2016 Jan;34:18-25
pubmed: 26615579
Crit Care. 2020 Apr 21;24(1):163
pubmed: 32317013
J Electrocardiol. 2010 Jul-Aug;43(4):302-9
pubmed: 20466388
Ann Card Anaesth. 2018 Jul-Sep;21(3):228-234
pubmed: 30052207
Epilepsy Res. 2015 Jan;109:48-56
pubmed: 25524842
Epilepsy Res. 2011 Aug;95(3):237-45
pubmed: 21561737
Epilepsia. 2016 Nov;57(11):1907-1915
pubmed: 27555091
Neurocrit Care. 2019 Oct;31(2):312-320
pubmed: 30788707
Epilepsy Res. 2010 Jun;90(1-2):157-63
pubmed: 20488665
J Clin Neurophysiol. 2015 Aug;32(4):324-30
pubmed: 26241242
Clin Drug Investig. 2014 Dec;34(12):879-86
pubmed: 25385363
Science. 1988 Jan 8;239(4836):162-9
pubmed: 3336779
Hell J Nucl Med. 2016 Sep-Dec;19(3):189-192
pubmed: 27824957
ARYA Atheroscler. 2013 Jan;9(1):7-10
pubmed: 23696753
Acta Neurochir Suppl. 2018;126:147-151
pubmed: 29492551
Indian J Crit Care Med. 2019 Jul;23(7):329-335
pubmed: 31406441
J Clin Neurophysiol. 2021 Jan 1;38(1):1-29
pubmed: 33475321
Seizure. 2014 Jan;23(1):55-61
pubmed: 24139618
Neurology. 2010 Oct 26;75(17):1501-8
pubmed: 20861452
J Neurol Neurosurg Psychiatry. 2005 Jun;76 Suppl 2:ii2-7
pubmed: 15961864
Int J Surg. 2014 Dec;12(12):1495-9
pubmed: 25046131
Neurosurgery. 2017 Jan 01;80(1):6-15
pubmed: 27654000