Management of Acute Myeloid Leukemia: Current Treatment Options and Future Perspectives.
AML
clinical trial
resistance
targeted therapy
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
16 Nov 2021
16 Nov 2021
Historique:
received:
25
10
2021
revised:
07
11
2021
accepted:
12
11
2021
entrez:
27
11
2021
pubmed:
28
11
2021
medline:
28
11
2021
Statut:
epublish
Résumé
Treatment of acute myeloid leukemia (AML) has improved in recent years and several new therapeutic options have been approved. Most of them include mutation-specific approaches (e.g., gilteritinib for AML patients with activating
Identifiants
pubmed: 34830877
pii: cancers13225722
doi: 10.3390/cancers13225722
pmc: PMC8616498
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
N Engl J Med. 2019 Jan 3;380(1):45-56
pubmed: 30501490
Cell Mol Life Sci. 2009 Apr;66(8):1326-36
pubmed: 19099185
Clin Cancer Res. 2016 Feb 15;22(4):868-76
pubmed: 26459177
Blood. 2018 Jan 25;131(4):468-471
pubmed: 29229596
N Engl J Med. 2018 Feb 1;378(5):439-448
pubmed: 29385370
Expert Opin Biol Ther. 2019 Jul;19(7):721-733
pubmed: 31286786
Blood. 2020 Feb 13;135(7):463-471
pubmed: 31841594
Blood. 2011 Aug 11;118(6):1504-15
pubmed: 21670473
Leuk Res. 2015 Feb;39(2):216-20
pubmed: 25533931
Cancer Discov. 2019 Jul;9(7):910-925
pubmed: 31048320
J Clin Oncol. 2021 Sep 1;39(25):2768-2778
pubmed: 34043428
Am J Hematol. 2020 Jul 6;:
pubmed: 32628327
Sci Transl Med. 2019 Oct 30;11(516):
pubmed: 31666400
Blood. 2013 Jun 6;121(23):4655-62
pubmed: 23613521
Nature. 2016 Oct 27;538(7626):477-482
pubmed: 27760111
Blood. 2012 Jun 21;119(25):6089-98
pubmed: 22446485
Blood. 2007 Apr 1;109(7):2985-8
pubmed: 17119119
Haematologica. 2019 Jan;104(1):113-119
pubmed: 30076173
Nat Cancer. 2020 Aug;1(8):826-839
pubmed: 33123685
Blood. 2013 Jun 13;121(24):4854-60
pubmed: 23591789
Cancer Cell. 2017 Dec 11;32(6):748-760.e6
pubmed: 29232553
N Engl J Med. 2017 Mar 2;376(9):836-847
pubmed: 28249141
Cancer Discov. 2019 Jul;9(7):890-909
pubmed: 31048321
Nat Rev Mol Cell Biol. 2014 Jan;15(1):49-63
pubmed: 24355989
Blood. 2020 Dec 24;136(26):3041-3050
pubmed: 33367545
Oncotarget. 2017 Oct 27;8(63):106948-106961
pubmed: 29291002
Nat Med. 2018 Dec;24(12):1859-1866
pubmed: 30420752
N Engl J Med. 2010 Aug 19;363(8):711-23
pubmed: 20525992
Am J Hematol. 2019 Aug;94(8):913-920
pubmed: 31145495
Haematologica. 2020 Mar;105(3):697-707
pubmed: 31123034
Future Oncol. 2020 May;16(13):807-815
pubmed: 32167393
Nat Genet. 2003 Jun;34(2):148-50
pubmed: 12717436
JAMA Oncol. 2018 Aug 1;4(8):1106-1110
pubmed: 29346478
Blood. 1998 Feb 1;91(3):991-1000
pubmed: 9446661
Blood Adv. 2020 May 12;4(9):1894-1905
pubmed: 32380538
Leukemia. 2011 Jul;25(7):1147-52
pubmed: 21494260
Cancer Discov. 2018 Dec;8(12):1566-1581
pubmed: 30185627
Lancet Oncol. 2018 Feb;19(2):216-228
pubmed: 29339097
Blood Cancer J. 2017 Mar 10;7(3):e542
pubmed: 28282031
Blood. 2021 Sep 30;138(13):1120-1136
pubmed: 34320168
Blood. 2009 Apr 9;113(15):3568-76
pubmed: 19204327
Front Oncol. 2021 Mar 11;11:649209
pubmed: 33777810
J Clin Oncol. 2017 Aug 10;35(23):2674-2682
pubmed: 28644774
Cancers (Basel). 2018 May 24;10(6):
pubmed: 29795051
Cancer Cell. 2010 Mar 16;17(3):225-34
pubmed: 20171147
Blood. 2020 Jun 11;135(24):2137-2145
pubmed: 32219442
Leukemia. 2013 Jun;27(6):1229-35
pubmed: 23314834
Ann Hematol. 2021 Apr;100(4):959-968
pubmed: 33191481
J Clin Oncol. 2021 May 10;39(14):1584-1594
pubmed: 33449813
Cancer Drug Resist. 2021;4:125-142
pubmed: 33796823
Oncotarget. 2015 Apr 20;6(11):9612-26
pubmed: 25823822
Leukemia. 2019 Jan;33(1):262-266
pubmed: 30008477
Oncotarget. 2017 Nov 3;8(63):107206-107222
pubmed: 29291023
Cancer Manag Res. 2019 Apr 23;11:3197-3213
pubmed: 31118772
Clin Cancer Res. 2019 Nov 15;25(22):6815-6826
pubmed: 31320594
N Engl J Med. 2019 Oct 31;381(18):1728-1740
pubmed: 31665578
J Clin Oncol. 2013 Dec 10;31(35):4424-30
pubmed: 24127442
Blood. 2001 Apr 15;97(8):2434-9
pubmed: 11290608
Blood. 2021 Feb 11;137(6):751-762
pubmed: 32929488
Biol Blood Marrow Transplant. 2018 Oct;24(10):2017-2024
pubmed: 29933073
Trends Biochem Sci. 2003 Jun;28(6):284-93
pubmed: 12826400
J Clin Oncol. 2019 May 20;37(15):1277-1284
pubmed: 30892988
Blood Cancer J. 2021 Feb 1;11(2):25
pubmed: 33563904
Mol Cancer Ther. 2011 Dec;10(12):2340-9
pubmed: 21914853
Blood. 2007 Mar 1;109(5):2264-5; author reply 2265
pubmed: 17312001
N Engl J Med. 2016 Nov 10;375(19):1823-1833
pubmed: 27718847
Leukemia. 1996 Dec;10(12):1911-8
pubmed: 8946930
Zhonghua Yi Xue Za Zhi. 2005 Jul 20;85(27):1903-6
pubmed: 16255985
Leukemia. 2017 Jan;31(1):1-10
pubmed: 27389053
Cancer Discov. 2016 Oct;6(10):1106-1117
pubmed: 27520294
Leuk Lymphoma. 2020 Feb;61(2):387-396
pubmed: 31545113
Cancer. 2021 Aug 15;127(16):2943-2953
pubmed: 33934351
Biol Blood Marrow Transplant. 2020 Dec;26(12):e322-e327
pubmed: 32866594
Nature. 2009 Dec 10;462(7274):739-44
pubmed: 19935646
Leukemia. 2021 Jul;35(7):1843-1863
pubmed: 33953290
Cancer Discov. 2017 Dec;7(12):1376-1393
pubmed: 29146569
Am J Hematol. 2015 Aug;90(8):732-6
pubmed: 26016821
Science. 2013 May 3;340(6132):626-30
pubmed: 23558169
Blood. 2007 May 1;109(9):4020-2
pubmed: 17202314
Leukemia. 2020 Nov;34(11):2858-2874
pubmed: 32651541
Blood. 2002 Oct 1;100(7):2393-8
pubmed: 12239147
Oncoimmunology. 2016 Jun 29;5(7):e1195535
pubmed: 27622049
Blood Adv. 2021 Sep 14;5(17):3279-3289
pubmed: 34459887
Leukemia. 2013 Feb;27(2):398-408
pubmed: 23103841
Blood. 2015 Jul 16;126(3):291-9
pubmed: 25987659
Int J Cancer. 2008 Jul 1;123(1):8-13
pubmed: 18425818
Lancet Oncol. 2020 Sep;21(9):1201-1212
pubmed: 32791048
Cancer Cell. 2010 Dec 14;18(6):553-67
pubmed: 21130701
Leukemia. 2008 Aug;22(8):1539-41
pubmed: 18528419
Leukemia. 2015 Jun;29(6):1290-300
pubmed: 25650089
Curr Med Chem. 2008;15(13):1274-87
pubmed: 18537607
Cancer Cell. 2006 May;9(5):351-65
pubmed: 16697956
N Engl J Med. 2016 Jun 9;374(23):2209-2221
pubmed: 27276561
J Exp Med. 2017 Feb;214(2):359-380
pubmed: 28031480
Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4622-7
pubmed: 23471998
Haematologica. 2021 Apr 01;106(4):1034-1046
pubmed: 32414851
Haematologica. 2018 Sep;103(9):e404-e407
pubmed: 29545346
Exp Hematol. 2008 Oct;36(10):1285-96
pubmed: 18640765
J Clin Oncol. 2020 Sep 10;38(26):2993-3002
pubmed: 32673171
Front Immunol. 2021 Apr 01;12:618710
pubmed: 33868234
Blood Adv. 2019 Jul 9;3(13):1939-1949
pubmed: 31253596
Blood. 2021 Jun 3;137(22):3093-3104
pubmed: 33598693
Nat Med. 2020 Sep;26(9):1459-1467
pubmed: 32601337
Blood Cancer J. 2012 Mar;2(3):e60
pubmed: 22829255
Blood. 2019 Feb 14;133(7):676-687
pubmed: 30510081
Clin Cancer Res. 2021 Jan 1;27(1):60-69
pubmed: 32998965
Clin Cancer Res. 2020 Dec 1;26(23):6132-6140
pubmed: 32998961
Nat Commun. 2020 Feb 17;11(1):928
pubmed: 32066721
Signal Transduct Target Ther. 2017 Apr 07;2:17012
pubmed: 29263915
Cell Stem Cell. 2015 Sep 3;17(3):341-52
pubmed: 26279267
Blood. 2009 Apr 23;113(17):4074-7
pubmed: 18483393
Haematologica. 2016 Nov;101(11):e457-e460
pubmed: 27418649
Leukemia. 2022 Jan;36(1):90-99
pubmed: 34316017
Leuk Lymphoma. 2021 Jun;62(6):1432-1440
pubmed: 33399480
Leukemia. 2019 Feb;33(2):379-389
pubmed: 30555165
Cancer Cell. 2011 Jan 18;19(1):138-52
pubmed: 21251617
Am J Hematol. 2020 Dec;95(12):1511-1521
pubmed: 32833294
Leukemia. 2021 Sep;35(9):2482-2495
pubmed: 34131281
N Engl J Med. 2009 Sep 10;361(11):1058-66
pubmed: 19657110
Nature. 2015 Aug 6;524(7563):114-8
pubmed: 26200337
J Clin Med. 2021 Apr 14;10(8):
pubmed: 33919958
Cancer Discov. 2017 May;7(5):478-493
pubmed: 28193778
Lancet Oncol. 2019 Jul;20(7):984-997
pubmed: 31175001
J Natl Compr Canc Netw. 2017 Jul;15(7):926-957
pubmed: 28687581
Nat Commun. 2018 Dec 17;9(1):5341
pubmed: 30559424
Blood. 2017 Jan 26;129(4):424-447
pubmed: 27895058
PLoS One. 2015 Aug 21;10(8):e0135520
pubmed: 26296092
Blood. 2009 Sep 17;114(12):2386-92
pubmed: 19602710
Leukemia. 2014 Jan;28(1):78-87
pubmed: 24045501
J Clin Oncol. 2012 Jul 20;30(21):2670-7
pubmed: 22689805
PLoS One. 2010 Feb 02;5(2):e9001
pubmed: 20126405
Lancet. 2012 Apr 21;379(9825):1508-16
pubmed: 22482940
Cancers (Basel). 2021 May 01;13(9):
pubmed: 34062779
Biology (Basel). 2021 Mar 24;10(4):
pubmed: 33804919
Mol Pharmacol. 2013 Sep;84(3):438-50
pubmed: 23814180
Cancer Cell. 2017 Oct 9;32(4):506-519.e5
pubmed: 29017060
Am J Hematol. 2018 Mar;93(3):401-407
pubmed: 29218851
Blood. 2021 Jul 29;138(4):318-330
pubmed: 34323938
Cell. 2009 Jul 23;138(2):286-99
pubmed: 19632179
Nat Commun. 2015 Oct 07;6:8489
pubmed: 26444494
N Engl J Med. 2020 Dec 24;383(26):2526-2537
pubmed: 33369355
Blood. 2003 Oct 1;102(7):2395-402
pubmed: 12805060
Curr Opin Genet Dev. 2007 Feb;17(1):23-30
pubmed: 17227708
Curr Cancer Drug Targets. 2020;20(7):490-500
pubmed: 32329690
Mol Cancer Ther. 2020 Sep;19(9):1875-1888
pubmed: 32518207
Am J Hematol. 2018 May 17;:
pubmed: 29770480
N Engl J Med. 2018 Jun 21;378(25):2386-2398
pubmed: 29860938
Nat Med. 2018 Mar;24(3):282-291
pubmed: 29431743
Nature. 2016 Dec 15;540(7633):433-437
pubmed: 27926740
Cell Death Differ. 2018 Jan;25(1):27-36
pubmed: 29099483
N Engl J Med. 2009 Feb 19;360(8):765-73
pubmed: 19228619
Biol Blood Marrow Transplant. 2016 Jul;22(7):1218-1226
pubmed: 27058617
Blood. 2020 Nov 19;136(21):2442-2456
pubmed: 32589720
Onco Targets Ther. 2019 Sep 11;12:7477-7488
pubmed: 31686853
Nature. 2018 Jul;559(7712):125-129
pubmed: 29950729
Blood Adv. 2019 Dec 23;3(24):4215-4227
pubmed: 31856268
Trends Biochem Sci. 2013 Aug;38(8):394-402
pubmed: 23850066
Cancers (Basel). 2020 Dec 12;12(12):
pubmed: 33322769
Blood. 2009 Jan 15;113(3):659-67
pubmed: 18931345
Am J Hematol. 2020 Sep;95(9):1006-1014
pubmed: 32390196
J Biol Chem. 2013 Feb 8;288(6):3804-15
pubmed: 23264629
Cell. 2009 Jul 23;138(2):271-85
pubmed: 19632178
Blood Cancer J. 2022 May 30;12(5):84
pubmed: 35637252
Leukemia. 2004 Jul;18(7):1223-30
pubmed: 15152266
J Clin Oncol. 2020 Feb 20;38(6):623-632
pubmed: 31851556
Semin Oncol. 2005 Oct;32(5):511-20
pubmed: 16210092
Blood. 2020 Mar 12;135(11):791-803
pubmed: 31932844
J Hematol Oncol. 2015 Oct 20;8:114
pubmed: 26483188
N Engl J Med. 2020 Aug 13;383(7):617-629
pubmed: 32786187
Clin Cancer Res. 2017 Nov 1;23(21):6430-6440
pubmed: 28765326
Front Oncol. 2021 May 03;11:659253
pubmed: 34012921
Blood. 2021 Sep 23;138(12):1067-1080
pubmed: 34115113
Blood. 2001 Oct 15;98(8):2301-7
pubmed: 11588023
N Engl J Med. 2017 Aug 3;377(5):454-464
pubmed: 28644114
Blood. 2020 Mar 5;135(10):713-723
pubmed: 31951650
Blood. 2002 Oct 1;100(7):2387-92
pubmed: 12239146
Blood. 2009 Apr 23;113(17):4063-73
pubmed: 19144992
Blood Adv. 2020 Oct 13;4(19):4945-4954
pubmed: 33049054