Entrapment of a Cytotoxic Drug into the Crystal Structure of Calcite for Targeted Drug Delivery.
MCF-7
calcite
in vitro
pH-responsiveness
target drug delivery
Journal
Materials (Basel, Switzerland)
ISSN: 1996-1944
Titre abrégé: Materials (Basel)
Pays: Switzerland
ID NLM: 101555929
Informations de publication
Date de publication:
09 Nov 2021
09 Nov 2021
Historique:
received:
22
09
2021
revised:
26
10
2021
accepted:
04
11
2021
entrez:
27
11
2021
pubmed:
28
11
2021
medline:
28
11
2021
Statut:
epublish
Résumé
Controlled drug release and targeted drug delivery can reduce systemic toxicity of chemotherapeutics by restricting drugs to the target organ and increasing the local concentration. As tumors and inflamed tissue are often surrounded by an acidic microenvironment, pH-responsive calcium carbonates (CaCO
Identifiants
pubmed: 34832137
pii: ma14226735
doi: 10.3390/ma14226735
pmc: PMC8622612
pii:
doi:
Types de publication
Journal Article
Langues
eng
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