Retinal Vascular Events after mRNA and Adenoviral-Vectored COVID-19 Vaccines-A Case Series.

COVID-19 vaccination post-vaccination retinal vascular complication vascular complication

Journal

Vaccines
ISSN: 2076-393X
Titre abrégé: Vaccines (Basel)
Pays: Switzerland
ID NLM: 101629355

Informations de publication

Date de publication:
17 Nov 2021
Historique:
received: 04 10 2021
revised: 05 11 2021
accepted: 11 11 2021
entrez: 27 11 2021
pubmed: 28 11 2021
medline: 28 11 2021
Statut: epublish

Résumé

To describe cases of retinal vascular events shortly after administration of mRNA or adenoviral-vectored COVID-19 vaccines. Retrospective, multicenter case series. Six cases of retinal vascular events shortly after receiving COVID-19 vaccines. A 38-year-old, otherwise healthy male patient presented with branch retinal arterial occlusion four days after receiving his second dose of SARS-CoV-2 vaccination with Comirnaty This case series describes six cases of retinal vascular events shortly after receiving mRNA or adenoviral-vectored COVID-19 vaccines. The short time span between received vaccination and occurrence of the observed retinal vascular events raises the question of a direct correlation. Our case series adds to further reports of possible side effects with potential serious post-immunization complications of COVID-19 vaccinations.

Sections du résumé

BACKGROUND BACKGROUND
To describe cases of retinal vascular events shortly after administration of mRNA or adenoviral-vectored COVID-19 vaccines.
DESIGN METHODS
Retrospective, multicenter case series.
METHODS METHODS
Six cases of retinal vascular events shortly after receiving COVID-19 vaccines.
RESULTS RESULTS
A 38-year-old, otherwise healthy male patient presented with branch retinal arterial occlusion four days after receiving his second dose of SARS-CoV-2 vaccination with Comirnaty
CONCLUSION CONCLUSIONS
This case series describes six cases of retinal vascular events shortly after receiving mRNA or adenoviral-vectored COVID-19 vaccines. The short time span between received vaccination and occurrence of the observed retinal vascular events raises the question of a direct correlation. Our case series adds to further reports of possible side effects with potential serious post-immunization complications of COVID-19 vaccinations.

Identifiants

pubmed: 34835280
pii: vaccines9111349
doi: 10.3390/vaccines9111349
pmc: PMC8625395
pii:
doi:

Types de publication

Case Reports

Langues

eng

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Auteurs

Christian Girbardt (C)

Department of Ophthalmology, University Hospital Leipzig Medical Center, 04103 Leipzig, Germany.

Catharina Busch (C)

Department of Ophthalmology, University Hospital Leipzig Medical Center, 04103 Leipzig, Germany.

Mayss Al-Sheikh (M)

Department of Ophthalmology, University Hospital Zurich, 8091 Zurich, Switzerland.

Jeanne Martine Gunzinger (JM)

Department of Ophthalmology, University Hospital Zurich, 8091 Zurich, Switzerland.

Alessandro Invernizzi (A)

Eye Clinic, Department of Biomedical and Clinical Sciences "Luigi Sacco", Luigi Sacco Hospital, University of Milan, 20157 Milan, Italy.
Save Sight Institute, Discipline of Ophthalmology, Sydney Medical School, The University of Sydney, Sydney, NSW 2000, Australia.

Alba Xhepa (A)

Eye Clinic, Department of Biomedical and Clinical Sciences "Luigi Sacco", Luigi Sacco Hospital, University of Milan, 20157 Milan, Italy.

Jan Darius Unterlauft (JD)

Department of Ophthalmology, University Hospital Leipzig Medical Center, 04103 Leipzig, Germany.
Department of Ophthalmology, University Hospital Bern, Inselspital, 3010 Bern, Switzerland.

Matus Rehak (M)

Department of Ophthalmology, University Hospital Leipzig Medical Center, 04103 Leipzig, Germany.

Classifications MeSH