Ciprofloxacin-Loaded Gold Nanoparticles against Antimicrobial Resistance: An In Vivo Assessment.

Enterococcus faecalis antibiotics antimicrobial resistance ciprofloxacin drug delivery gold nanoparticles liver and kidney infections nanotechnology

Journal

Nanomaterials (Basel, Switzerland)
ISSN: 2079-4991
Titre abrégé: Nanomaterials (Basel)
Pays: Switzerland
ID NLM: 101610216

Informations de publication

Date de publication:
22 Nov 2021
Historique:
received: 22 08 2021
revised: 04 11 2021
accepted: 06 11 2021
entrez: 27 11 2021
pubmed: 28 11 2021
medline: 28 11 2021
Statut: epublish

Résumé

Metallic nanoparticles, such as gold nanoparticles (AuNPs), have been extensively studied as drug delivery systems for various therapeutic applications. However, drug-loaded-AuNPs have been rarely explored in vivo for their effect on bacteria residing inside tissues. Ciprofloxacin (CIP) is a second-generation fluoroquinolone with a broad-spectrum of antibiotic properties devoid of developing bacteria resistance. This research is focused on the synthesis and physical characterization of Ciprofloxacin-loaded gold nanoparticles (CIP-AuNPs) and their effect on the colonization of

Identifiants

pubmed: 34835916
pii: nano11113152
doi: 10.3390/nano11113152
pmc: PMC8620493
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Higher Education Commission, Pakistan
ID : 6035

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Auteurs

Afrah Nawaz (A)

Department of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.

Syed Mohsin Ali (SM)

Department of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.

Nosheen Fatima Rana (NF)

Department of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.

Tahreem Tanweer (T)

Department of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.

Amna Batool (A)

Department of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.

Thomas J Webster (TJ)

Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA.

Farid Menaa (F)

Departments of Internal Medicine and Nanomedicine, California Innovations Corporation, San Diego, CA 92037, USA.

Sundus Riaz (S)

Department of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.

Zahra Rehman (Z)

Department of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.

Farhat Batool (F)

Department of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.

Misha Fatima (M)

Department of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.

Tuba Maryam (T)

Department of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.

Iqra Shafique (I)

Department of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.

Abida Saleem (A)

Department of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.

Arfa Iqbal (A)

Department of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.

Classifications MeSH