The Effect of Weight-Loss Interventions on Cervical and Chin Subcutaneous Fat Depots; the CENTRAL Randomized Controlled Trial.


Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
27 Oct 2021
Historique:
received: 24 09 2021
revised: 24 10 2021
accepted: 26 10 2021
entrez: 27 11 2021
pubmed: 28 11 2021
medline: 17 12 2021
Statut: epublish

Résumé

Accumulation of cervical and chin subcutaneous adipose tissues (SAT) represent known phenotypes of obesity. We aimed to evaluate the sensitivity of these fat storages to long-term weight-loss directed lifestyle-intervention and to assess their relations to bodily-adiposity, insulin-resistance, and cardiometabolic risk; We randomly assigned 278 participants with abdominal-obesity/dyslipidemia to low-fat or Mediterranean/low-carbohydrate diets +/- physical-activity. All participants underwent an 18 month whole-body magnetic resonance imaging follow-up, from which we assessed cervical and chin SAT-areas; Participants (age = 48 years; 90% men; body-mass-index = 30.9 kg/m

Identifiants

pubmed: 34836081
pii: nu13113827
doi: 10.3390/nu13113827
pmc: PMC8617936
pii:
doi:

Substances chimiques

Cholesterol, HDL 0
Triglycerides 0

Banques de données

ClinicalTrials.gov
['NCT01530724']

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Deutsche Forschungsgemeinschaft
ID : SFB1052
Organisme : Israel Ministry of Science and Technology
ID : 3-13604
Organisme : CSRD VA
ID : 1
Pays : United States

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Auteurs

Gal Tsaban (G)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.
Department of Cardiology, Soroka University Medical Center, Beer-Sheva 84101, Israel.

Avital Bilitzky-Kopit (A)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.

Anat Yaskolka Meir (A)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.

Hila Zelicha (H)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.

Yftach Gepner (Y)

Department of Epidemiology and Preventive Medicine, Sackler Faculty of Medicine, and Sylvan Adams Sports Institute, School of Public Health, Tel-Aviv University, Tel-Aviv 96678, Israel.

Ilan Shelef (I)

Division of Clinical Radiology, Soroka University Medical Center, Beer-Sheva 84101, Israel.

Omri Orr (O)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.

Yoash Chassidim (Y)

Research Center, Soroka University Medical Center, Beer-Sheva 84101, Israel.

Benjamin Sarusi (B)

Department of Medicine, Nuclear Research Center Negev, Dimona 84190, Israel.

Uta Ceglarek (U)

Department of Medicine, University of Leipzig, 04103 Leipzig, Germany.

Michael Stumvoll (M)

Department of Medicine, University of Leipzig, 04103 Leipzig, Germany.

Matthias Blüher (M)

Department of Medicine, University of Leipzig, 04103 Leipzig, Germany.

Meir J Stampfer (MJ)

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.

Iris Shai (I)

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.

Dan Schwarzfuchs (D)

Department of Medicine, Nuclear Research Center Negev, Dimona 84190, Israel.
Emergency Medicine Division, Soroka University Medical Center, Beer-Sheva 84101, Israel.

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