State regulation positively impacts opioid prescribing patterns in ankle fracture surgery: A national and state-level analysis.


Journal

Injury
ISSN: 1879-0267
Titre abrégé: Injury
Pays: Netherlands
ID NLM: 0226040

Informations de publication

Date de publication:
Feb 2022
Historique:
received: 20 01 2021
revised: 12 11 2021
accepted: 14 11 2021
pubmed: 28 11 2021
medline: 8 2 2022
entrez: 27 11 2021
Statut: ppublish

Résumé

The impact of time and state regulation on opioid prescribing in orthopedic trauma is not well known. The purpose of this study is to evaluate the impact of time and state-level opioid legislation on 90-day perioperative opioid prescribing in ankle fracture surgery from 2010 to 2019. This is a retrospective, cohort study using a national insurance database including commercial insurance, Medicare, Medicaid, and cash pay patients to evaluate 30-day pre-operative to 90-day post-operative opioid prescription filling in 40,286 patients ages 18 and older undergoing Current Procedural Terminology codes 27,766, 27,769, 27,792, 27,814, 27,822, and/or 27,823 between 2010 and 2019 in all 50 United States. The primary study outcome was initial and cumulative perioperative opioid prescription filling and rates of filling and refills over the study timeframe. Mean first prescription volume has not changed dramatically from 2010 (37 oxycodone 5 mg pills) to 2019 (33.3 oxycodone 5 mg pills). However, cumulative prescriptions within the 30PRE-90POST timeframe have decreased considerably from 2010 (128.5 oxycodone 5 mg pills) to 2019 (70.4 oxycodone 5 mg pills), and cumulative prescription filling in years 2018 and 2019 was significantly less than in 2010. Legislation targeting duration or duration and volume had the largest impacts on initial and cumulative opioid prescribing. In ankle fracture surgery, states with opioid prescribing legislation had larger reductions in perioperative opioid prescribing compared to states without opioid legislation. Legislation targeting duration or duration and volume had the largest impacts on opioid prescribing. Level III, Retrospective prognostic cohort study.

Sections du résumé

BACKGROUND BACKGROUND
The impact of time and state regulation on opioid prescribing in orthopedic trauma is not well known. The purpose of this study is to evaluate the impact of time and state-level opioid legislation on 90-day perioperative opioid prescribing in ankle fracture surgery from 2010 to 2019.
METHODS METHODS
This is a retrospective, cohort study using a national insurance database including commercial insurance, Medicare, Medicaid, and cash pay patients to evaluate 30-day pre-operative to 90-day post-operative opioid prescription filling in 40,286 patients ages 18 and older undergoing Current Procedural Terminology codes 27,766, 27,769, 27,792, 27,814, 27,822, and/or 27,823 between 2010 and 2019 in all 50 United States. The primary study outcome was initial and cumulative perioperative opioid prescription filling and rates of filling and refills over the study timeframe.
RESULTS RESULTS
Mean first prescription volume has not changed dramatically from 2010 (37 oxycodone 5 mg pills) to 2019 (33.3 oxycodone 5 mg pills). However, cumulative prescriptions within the 30PRE-90POST timeframe have decreased considerably from 2010 (128.5 oxycodone 5 mg pills) to 2019 (70.4 oxycodone 5 mg pills), and cumulative prescription filling in years 2018 and 2019 was significantly less than in 2010. Legislation targeting duration or duration and volume had the largest impacts on initial and cumulative opioid prescribing.
CONCLUSIONS CONCLUSIONS
In ankle fracture surgery, states with opioid prescribing legislation had larger reductions in perioperative opioid prescribing compared to states without opioid legislation. Legislation targeting duration or duration and volume had the largest impacts on opioid prescribing.
LEVEL OF EVIDENCE METHODS
Level III, Retrospective prognostic cohort study.

Identifiants

pubmed: 34836628
pii: S0020-1383(21)00946-3
doi: 10.1016/j.injury.2021.11.039
pii:
doi:

Substances chimiques

Analgesics, Opioid 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

445-452

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest None.

Auteurs

Daniel J Cunningham (DJ)

Duke University Department of Orthopaedic Surgery, 311 Trent Drive, Durham, NC 27710, United States. Electronic address: danieljocunningham@gmail.com.

Michael Blatter (M)

Duke University Department of Orthopaedic Surgery, 311 Trent Drive, Durham, NC 27710, United States.

Samuel B Adams (SB)

Duke University Department of Orthopaedic Surgery, 311 Trent Drive, Durham, NC 27710, United States.

Mark J Gage (MJ)

Duke University Department of Orthopaedic Surgery, 311 Trent Drive, Durham, NC 27710, United States.

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Classifications MeSH