Concomitantly discovered visceral artery aneurysms do rarely grow during cancer therapy.
aneurysm growth
chemotherapy
visceral artery aneurysm
Journal
Clinical anatomy (New York, N.Y.)
ISSN: 1098-2353
Titre abrégé: Clin Anat
Pays: United States
ID NLM: 8809128
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
revised:
16
11
2021
received:
28
08
2021
accepted:
21
11
2021
pubmed:
28
11
2021
medline:
16
3
2022
entrez:
27
11
2021
Statut:
ppublish
Résumé
Visceral artery aneurysms (VAA) are a rare entity of arterial aneurysms with the imminent threat of rupture. The impact of cancer and chemotherapy on the growth of VAAs is unknown. A retrospective dual center cohort study of patients with concomitant VAA and different types of cancer was conducted and the impact of various chemotherapeutic agents on VAA growth was studied by sequential CT analysis. For comparison, a non-cancer all comer cohort with VAAs and no cancer was studied to compare different growth rates. The primary endpoint was aneurysm progress or regression >1.75 mm. Chi-square test, Fisher's exact test and Mann-Whitney test was used for statistical comparison. In the 17-year-period from January 2003 to March 2020, 59 patients with 30 splenic artery aneurysms, 14 celiac trunk aneurysms, 11 renal artery aneurysms and 4 other VAA and additional malignancy were identified. 20% of patients suffered from prostate cancer, the rest were heterogeneous. The most prevalent chemotherapies were alkylating agents (23%), antimetabolites (14%) and mitose inhibitors (10%). Eight patients had relevant growth of their VAA and one patient showed diameter regression (average growth rate 0.1 ± 0.5 mm/year). Twenty-nine patients with 14 splenic, 11 RAAs (seven right) and 4 celiac trunk aneurysms were available in the non-cancer comparison cohort (average growth rate 0.5 ± 0.9 mm/year, p = 0.058). However, the growth rate of patients receiving operative treatment for relevant VAA growth was significantly higher (p = 0.004). VAAs grow rarely, and rather slow. Cancer and/or chemotherapy do not significantly influence the annual growth rate. Additional control examinations seem unnecessary.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
296-304Informations de copyright
© 2022 The Authors. Clinical Anatomy published by Wiley Periodicals LLC on behalf of American Association of Clinical Anatomists.
Références
Barrionuevo, P., Malas, M. B., Nejim, B., Haddad, A., Morrow, A., Ponce, O., Hasan, B., Seisa, M., Chaer, R., & Murad, M. H. (2019). A systematic review and meta-analysis of the management of visceral artery aneurysms. Journal of Vascular Surgery, 70(5), 1694-1699. https://doi.org/10.1016/j.jvs.2019.02.024
Batagini, N. C., Constantin, B. D., Kirksey, L., Vallentsits Estenssoro, A. E., Puech-Leao, P., De Luccia, N., & Simao da Silva, E. (2020). Natural history of splanchnic artery aneurysms. Annals of Vascular Surgery. 73, 290-295. https://doi.org/10.1016/j.avsg.2020.10.047
Baudino, T. A. (2015). Targeted cancer therapy: The next generation of cancer treatment. Current Drug Discovery Technologies, 12(1), 3-20. https://doi.org/10.2174/1570163812666150602144310
Belli, A. M., Markose, G., & Morgan, R. (2012). The role of interventional radiology in the management of abdominal visceral artery aneurysms. Cardiovascular and Interventional Radiology, 35(2), 234-243. https://doi.org/10.1007/s00270-011-0201-3
Björck, M., Koelemay, M., Acosta, S., Bastos Goncalves, F., Kölbel, T., Kolkman, J. J., Lefevre, J. H., Lees, T., Menyhei, G., Oderich, G., Esvs Guidelines Committee, Kolh, P., de Borst, G. J., Chakfe, N., Debus, S., Hinchliffe, R., Kakkos, S., Koncar, I., Sanddal Lindholt, J., … Naylor, R. (2017). Editor's choice-Management of the Diseases of mesenteric arteries and veins: Clinical practice guidelines of the European Society of Vascular Surgery (ESVS). European Journal of Vascular and Endovascular Surgery, 53(4), 460-510. https://doi.org/10.1016/j.ejvs.2017.01.010
Busch, A., Grimm, C., Hartmann, E., Paloschi, V., Kickuth, R., Lengquist, M., Eriksson, P., Otto, C., Kellersmann, R., Lorenz, U., & Maegdefessel, L. (2017). Vessel wall morphology is equivalent for different artery types and localizations of advanced human aneurysms. Histochemistry and Cell Biology, 148, 425-433. https://doi.org/10.1007/s00418-017-1575-3
Busch, A., Pauli, J., Winski, G., Bleichert, S., Chernogubova, E., Metschl, S., Winter, H., Trenner, M., Wiegering, A., Otto, C., Fischer, J., Reiser, J., Werner, J., Roy, J., Brostjan, C., Knappich, C., Eckstein, H. H., Paloschi, V., & Maegdefessel, L. (2021). Lenvatinib halts aortic aneurysm growth by restoring smooth muscle cell contractility. JCI Insight, 6(15), e140364. https://doi.org/10.1172/jci.insight.140364
Chaer, R. A., Abularrage, C. J., Coleman, D. M., Eslami, M. H., Kashyap, V. S., Rockman, C., & Murad, M. H. (2020). The society for vascular surgery clinical practice guidelines on the management of visceral aneurysms. Journal of Vascular Surgery, 72(1S), 3S-39S. https://doi.org/10.1016/j.jvs.2020.01.039
Febres-Aldana, C. A., Castellano-Sanchez, A. A., & Alexis, J. (2019). Spontaneous perforation of small intestine followed by rupture of the cystic artery: The natural history of Vascular Ehlers-Danlos Syndrome. Autopsy & Case Reports, 9(1), e2018054. https://doi.org/10.4322/acr.2018.054
Gotwals, P., Cameron, S., Cipolletta, D., Cremasco, V., Crystal, A., Hewes, B., Mueller, B., Quaratino, S., Sabatos-Peyton, C., Petruzzelli, L., Engelman, J. A., & Dranoff, G. (2017). Prospects for combining targeted and conventional cancer therapy with immunotherapy. Nature Reviews. Cancer, 17(5), 286-301. https://doi.org/10.1038/nrc.2017.17
Hultgren, R., Elfstrom, K. M., Ohman, D., & Linne, A. (2020). Long-term follow-up of men invited to participate in a population-based abdominal aortic aneurysm screening program. Angiology, 71(7), 641-649. https://doi.org/10.1177/0003319720921741
Martin, Z. L., Mastracci, T. M., Greenberg, R. K., Morales, J. P., & Bena, J. (2015). The effect of chemotherapy for malignancy on the natural history of aortic aneurysm. Journal of Vascular Surgery, 61(1), 50-57. https://doi.org/10.1016/j.jvs.2014.06.123
Maxwell, D. W., Kenney, L., Sarmiento, J. M., & Rajani, R. R. (2021). Aortic aneurysm natural progression is not influenced by concomitant malignancy and chemotherapy. Annals of Vascular Surgery, 71, 29-39. https://doi.org/10.1016/j.avsg.2020.08.137
Obara, H., Kentaro, M., Inoue, M., & Kitagawa, Y. (2020). Current management strategies for visceral artery aneurysms: An overview. Surgery Today, 50(1), 38-49. https://doi.org/10.1007/s00595-019-01898-3
Obata, K., Sugitani, I., Ebina, A., Sugiura, Y., Toda, K., Takahashi, S., & Kawabata, K. (2016). Common carotid artery rupture during treatment with lenvatinib for anaplastic thyroid cancer. International Cancer Conference Journal, 5(4), 197-201. https://doi.org/10.1007/s13691-016-0257-7
Oshima, Y., Tanimoto, T., Yuji, K., & Tojo, A. (2017). Association between aortic dissection and systemic exposure of vascular endothelial growth factor pathway inhibitors in the Japanese adverse drug event report database. Circulation, 135(8), 815-817. https://doi.org/10.1161/CIRCULATIONAHA.116.025144
Pesce, A., Palmieri, M., Zancana, G., Salvati, M., Santoro, A., Raco, A., & Frati, A. (2020). Radiation-induced brain aneurysms: Institutional experience and state of the art in the contemporary literature. World Neurosurgery, 135, 339-351. https://doi.org/10.1016/j.wneu.2019.09.157
Pitton, M. B., Dappa, E., Jungmann, F., Kloeckner, R., Schotten, S., Wirth, G. M., Mittler, J., Lang, H., Mildenberger, P., Kreitner, K. F., Oberholzer, K., & Dueber, C. (2015). Visceral artery aneurysms: Incidence, management, and outcome analysis in a tertiary care center over one decade. European Radiology, 25(7), 2004-2014. https://doi.org/10.1007/s00330-015-3599-1
Rajiah, P. (2020). Updates in vascular computed tomography. Radiologic Clinics of North America, 58(4), 671-691. https://doi.org/10.1016/j.rcl.2020.02.011
Selo-Ojeme, D. O., & Welch, C. C. (2003). Review: Spontaneous rupture of splenic artery aneurysm in pregnancy. European Journal of Obstetrics, Gynecology, and Reproductive Biology, 109(2), 124-127. https://doi.org/10.1016/s0301-2115(03)00094-0
Shimohira, M., Kondo, H., Ogawa, Y., Kawada, H., Koganemaru, M., Ikeda, O., Yamamoto, A., Komada, T., Tanoue, S., Muraoka, N., Tanikake, M., Hayashi, S., Yamamoto, S., Sato, T., Mizunuma, K., Ganaha, F., Murakami, Y., & Ishiguchi, T. (2021). Natural history of unruptured visceral artery aneurysms due to segmental arterial mediolysis and efficacy of transcatheter arterial embolization: A retrospective multiinstitutional study in Japan. AJR. American Journal of Roentgenology, 216(3), 691-697. https://doi.org/10.2214/AJR.19.22547
Sousa, J., Costa, D., & Mansilha, A. (2019). Visceral artery aneurysms: Review on indications and current treatment strategies. International Angiology, 38(5), 381-394. https://doi.org/10.23736/S0392-9590.19.04194-4
Sweeting, M. J., Thompson, S. G., Brown, L. C., Powell, J. T., & RESCAN Collaborators. (2012). Meta-analysis of individual patient data to examine factors affecting growth and rupture of small abdominal aortic aneurysms. The British Journal of Surgery, 99(5), 655-665. https://doi.org/10.1002/bjs.8707
Thompson, S. G., Brown, L. C., Sweeting, M. J., Bown, M. J., Kim, L. G., Glover, M. J., Buxton, M. J., & Powell, J. T. (2013). Systematic review and meta-analysis of the growth and rupture rates of small abdominal aortic aneurysms: Implications for surveillance intervals and their cost-effectiveness. Health Technology Assessment, 17(41), 1-118. https://doi.org/10.3310/hta17410
Vorkapic, E., Dugic, E., Vikingsson, S., Roy, J., Mayranpaa, M. I., Eriksson, P., & Wagsater, D. (2016). Imatinib treatment attenuates growth and inflammation of angiotensin II induced abdominal aortic aneurysm. Atherosclerosis, 249, 101-109. https://doi.org/10.1016/j.atherosclerosis.2016.04.006
Wanhainen, A., Verzini, F., Van Herzeele, I., Allaire, E., Bown, M., Cohnert, T., & Verhagen, H. (2019). Editor's choice-European Society for Vascular Surgery (ESVS) 2019 clinical practice guidelines on the Management of Abdominal Aorto-iliac Artery Aneurysms. European Journal of Vascular and Endovascular Surgery, 57(1), 8-93. https://doi.org/10.1016/j.ejvs.2018.09.020
Wayne, E. J., Edwards, M. S., Stafford, J. M., Hansen, K. J., & Corriere, M. A. (2014). Anatomic characteristics and natural history of renal artery aneurysms during longitudinal imaging surveillance. Journal of Vascular Surgery, 60(2), 448-452. https://doi.org/10.1016/j.jvs.2014.03.006
Wohlauer, M., McKenney, J. K., & Park, W. M. (2016). Postradiation extraskeletal osteosarcoma masquerading as an axillary artery Pseudoaneurysm. Annals of Vascular Surgery, 30(157), e157-e159. https://doi.org/10.1016/j.avsg.2015.06.069