Retinal optical coherence tomography angiography findings of acute anterior uveitis.
Anterior uveitis
Foveal avascular zone
Microvasculature
OCTA
Optical coherence tomography angiography
Vessel density
Journal
International ophthalmology
ISSN: 1573-2630
Titre abrégé: Int Ophthalmol
Pays: Netherlands
ID NLM: 7904294
Informations de publication
Date de publication:
May 2022
May 2022
Historique:
received:
30
05
2021
accepted:
12
11
2021
pubmed:
28
11
2021
medline:
25
5
2022
entrez:
27
11
2021
Statut:
ppublish
Résumé
To evaluate the changes in retinal microvasculature in eyes with anterior uveitis (AU) using optical coherence tomography angiography. Foveal avascular zone (FAZ) of superficial capillary plexus (SCP) and deep capillary plexus (DCP), vessel density (VD) of SCP, DCP, and choriocapillaris, and central macular thickness (CMT) and central foveal thickness (CFT) were calculated from 34 healthy and 41 uveitic eyes. The parameters were compared between the two groups. The deep FAZ was significantly smaller in the eyes with AU during the attack than after recovery and the control group (p = 0.001 and p = 0.003, respectively). The VD in deep capillary plexus (DCP) in eyes with AU during the attack was significantly higher than the control group (p = 0.048). The VD in the foveal sector of DCP in eyes with AU during the attack and after recovery was significantly higher than the control group (p = 0.001 and p = 0.031, respectively). There was no significant difference regarding CMT, CFT, VDs of each segment and each sector, and superficial and deep FAZ between eyes with first uveitis attack and those with recurrent uveitis during the attack and after recovery (p > 0.05). The results of this study show that there is a reduction in the FAZ and an increase in the VD of the DCP of the retina during active AU, and these findings are reversible. Acute AU may affect the macular microvasculature, which is usually temporary, especially in the DCP.
Identifiants
pubmed: 34837592
doi: 10.1007/s10792-021-02129-w
pii: 10.1007/s10792-021-02129-w
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1409-1418Informations de copyright
© 2021. The Author(s), under exclusive licence to Springer Nature B.V.
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