Differences in olfactory habituation between orthonasal and retronasal pathways.
Habituation
Orthonasal olfaction
Phenethyl alcohol
Retronasal olfaction
n-Butyl acetate
Journal
The journal of physiological sciences : JPS
ISSN: 1880-6562
Titre abrégé: J Physiol Sci
Pays: Japan
ID NLM: 101262417
Informations de publication
Date de publication:
27 Nov 2021
27 Nov 2021
Historique:
received:
18
09
2021
accepted:
15
11
2021
entrez:
28
11
2021
pubmed:
29
11
2021
medline:
14
1
2022
Statut:
epublish
Résumé
The odorant arrives at nasal olfactory epithelium ortho- and retronasally. This experiment aimed to study the potential different olfactory habituation in orthonasal and retronasal pathways. 68 subjects were stimulated by constant airflow with an odor (50% phenethyl alcohol, PEA or 5% n-butyl acetate, BA) presented ortho- or retronasally. Participants rated the perceived odor intensity (0-10 points) per minute until the odor sensation disappeared. We also investigated the cross-habituation: when the subjects achieved full habituation, continue to rate odor intensity in a different pathway after instantly switching the odor stimulation pathway. The olfactory habituation curve was drawn. The differences of ratings between the orthonasal and retronasal olfaction at different time points and between male and female subjects were analyzed. The two odor intensity ratings decreased as the time extended, share the same "fast followed by slow" type. The ratings of orthonasal olfaction decreased faster than that of retronasal. The intensity rating of PEA of male retronasal approach was lower than that of female at the 5th min (p = 0.018). When orthonasal full habituation achieved, there was significant difference between the intensity ratings and the initial ratings of the retronasal stimulation pathway (p < 0.0001), and vice versa. We found obvious habituation as well as cross-habituation in both orthonasal and retronasal olfaction. The habituation of orthonasal olfaction was faster than that of retronasal olfaction. These different habituations were related to the gender.
Identifiants
pubmed: 34837939
doi: 10.1186/s12576-021-00822-0
pii: 10.1186/s12576-021-00822-0
pmc: PMC10716942
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
36Subventions
Organisme : Beijing Scholars Program
ID : No.051
Organisme : Clinical Research and Development Project of Zhongnan Hospital of Wuhan University
ID : lcyf202102
Organisme : Beijing Municipal Administration of Hospitals
ID : PX2020026
Informations de copyright
© 2021. The Author(s).
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