Precision medicine in secondary prevention of ischemic stroke: how may blood-based biomarkers help in clinical routine? An expert opinion.


Journal

Current opinion in neurology
ISSN: 1473-6551
Titre abrégé: Curr Opin Neurol
Pays: England
ID NLM: 9319162

Informations de publication

Date de publication:
01 02 2022
Historique:
pubmed: 29 11 2021
medline: 29 1 2022
entrez: 28 11 2021
Statut: ppublish

Résumé

One in eight patients unfortunately suffers a new stroke within 5 years of their first stroke, even today. Research in precision medicine could lead to a more individualized treatment allocation, possibly achieving lower recurrence rates of ischemic stroke. In this narrative review, we aim to discuss potential clinical implementation of several promising candidate blood biomarkers. We discuss specifically some promising blood-based biomarkers, which may improve the identification of underlying causes as well as risk stratification of patients according to their specific cerebrovascular risk factor pattern. Multimodal profiling of ischemic stroke patients by means of blood biomarkers, in addition to established clinical and neuroradiological data, may allow in the future a refinement of decision algorithms for treatment allocation in secondary ischemic stroke prevention.

Identifiants

pubmed: 34839341
doi: 10.1097/WCO.0000000000001011
pii: 00019052-202202000-00009
doi:

Substances chimiques

Biomarkers 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

45-54

Informations de copyright

Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

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Auteurs

Giulio Bicciato (G)

Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.

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