Diabetes as a predictive factor for severe form and high mortality risk of COVID-19: Retrospective cohort study of 188 cases.

COVID-19 Diabetes Mortality Predictive factors Sevirity

Journal

Annals of medicine and surgery (2012)
ISSN: 2049-0801
Titre abrégé: Ann Med Surg (Lond)
Pays: England
ID NLM: 101616869

Informations de publication

Date de publication:
Dec 2021
Historique:
received: 20 09 2021
revised: 18 11 2021
accepted: 20 11 2021
pubmed: 30 11 2021
medline: 30 11 2021
entrez: 29 11 2021
Statut: ppublish

Résumé

Since the appearance of the first case of the SARS CoV 2 infection, several studies have been conducted to identify the predictive factors of mortality in patients with COVID-19. According to previous reports, diabetes seems to be associated with severe clinical forms of the new coronavirus (SARS CoV 2).Our study aimed to identify the epidemiological, clinical, radiological and prognostic profile of diabetic patients with COVID-19. This retrospective study included diabetic patients diagnosed with COVID-19 and admitted to the Resuscitation Department of our university hospital center From Mars 1st 2020, to December 31st, 2020. In this study, we collected the data of 600 patients admitted to the Anesthesia and Resuscitation Department of the Mohammed VI University Hospital of Oujda, a group of 188 (31.3%) had diabetes.The median age of our patients was 67 [25-75]. Were noted in the majority, of patients 69.6% with diabetes have developed a severe or critical injuries in the Chest CT Scan. Furthermore, we found that the mortality rate in this category of patients was higher 65/188 (34.60%) compared to non-diabetic patients, 130/412 (31.60%) (34.60%vs 31.60%; p: 0.464). Based on the results of this retrospective study, we concluded that diabetes is predictive factor for the need of an intensive care as well as a high risk of mortality related to COVID-19.Practically speaking, diabetic patients should be monitored more closely and need an aggressive preventive management protocols in order to prevent severe forms of the disease and a drastic evolution.More research is direly needed to identify patients of a higher risk of developing severe forms of COVID-19.

Identifiants

pubmed: 34840736
doi: 10.1016/j.amsu.2021.103095
pii: S2049-0801(21)01045-1
pmc: PMC8609669
doi:

Types de publication

Journal Article

Langues

eng

Pagination

103095

Informations de copyright

© 2021 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd.

Déclaration de conflit d'intérêts

We have no conflicts of interest.

Références

Lancet. 2020 Feb 15;395(10223):470-473
pubmed: 31986257
Diabetes Metab Res Rev. 2020 Mar 31;:e3319
pubmed: 32233013
Diabetes Obes Metab. 2020 Oct;22(10):1897-1906
pubmed: 32469464
Diabetes Res Clin Pract. 2020 Nov;169:108467
pubmed: 32979419
Prim Care Diabetes. 2021 Dec;15(6):918-922
pubmed: 34393092
Front Endocrinol (Lausanne). 2021 Jun 17;12:649525
pubmed: 34220706
Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Feb 10;41(2):145-151
pubmed: 32064853
J Diabetes. 2021 Feb;13(2):177-178
pubmed: 33107708
Diabetes Metab Syndr. 2020 Jul - Aug;14(4):303-310
pubmed: 32298981
Int J Surg. 2019 Dec;72:156-165
pubmed: 31704426
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264

Auteurs

Sara Berrajaa (S)

Anesthesia and Resuscitation Department, MOHAMMED VI University Hospital Center, Oujda, Morocco.

Samia Berrichi (S)

Anesthesia and Resuscitation Department, MOHAMMED VI University Hospital Center, Oujda, Morocco.

Zakaria Bouayed (Z)

Anesthesia and Resuscitation Department, MOHAMMED VI University Hospital Center, Oujda, Morocco.

Sanae El Mezzeoui (SE)

Anesthesia and Resuscitation Department, MOHAMMED VI University Hospital Center, Oujda, Morocco.

Fatima Zahra Aftiss (FZ)

Anesthesia and Resuscitation Department, MOHAMMED VI University Hospital Center, Oujda, Morocco.

Houssam Bkiyar (H)

Anesthesia and Resuscitation Department, MOHAMMED VI University Hospital Center, Oujda, Morocco.
Simulation Center, Faculty of Medicine and Pharmacy, Oujda, Morocco.

Naima Abda (N)

Laboratory of Epidemiology, Clinical Research and Public Health LERCSP, Faculty of Medicine and Pharmacy, Oujda, Morocco.

Brahim Housni (B)

Anesthesia and Resuscitation Department, MOHAMMED VI University Hospital Center, Oujda, Morocco.
Simulation Center, Faculty of Medicine and Pharmacy, Oujda, Morocco.

Classifications MeSH