Systemic sclerosis cutaneous expression: Management of skin fibrosis and digital ulcers.

Autologous fat grafting DU, digital ulcer Digital ulcers MHISS, Mouth Handicap in Systemic Sclerosis scale ROM, Range of Motion RP, Raynaud's phenomenon SSc, Systemic sclerosis SU, skin ulcer Scleroderma Skin fibrosis Systemic sclerosis

Journal

Annals of medicine and surgery (2012)
ISSN: 2049-0801
Titre abrégé: Ann Med Surg (Lond)
Pays: England
ID NLM: 101616869

Informations de publication

Date de publication:
Nov 2021
Historique:
received: 30 07 2021
revised: 25 10 2021
accepted: 28 10 2021
entrez: 29 11 2021
pubmed: 30 11 2021
medline: 30 11 2021
Statut: epublish

Résumé

Systemic sclerosis is a connective tissue disease with cutaneous involvement. Clinical manifestations result from the balance of inflammations/autoimmunity process and fibrogenesis. Patients suffer from skin ulcers, non-ulcerative lesions including digital pitting scars, telangiectasias, subungual hyperkeratosis, abrasions, fissures, and subcutaneous calcinosis. A review about the pathophysiology of the disease, the physical examination of the patients, the instrumental assessment, and possible treatments is performed.

Identifiants

pubmed: 34840747
doi: 10.1016/j.amsu.2021.102984
pii: S2049-0801(21)00934-1
pmc: PMC8606707
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

102984

Informations de copyright

© 2021 The Authors.

Déclaration de conflit d'intérêts

The authors declares that there is no conflict of interest regarding the publication of this paper.

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Auteurs

Marta Starnoni (M)

Department of Medical and Surgical Sciences, Division of Plastic Surgery, University of Modena and Reggio Emilia, Policlinico of Modena, Largo Pozzo 71, 41124, Modena, Italy.
Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy.

Marco Pappalardo (M)

Department of Medical and Surgical Sciences, Division of Plastic Surgery, University of Modena and Reggio Emilia, Policlinico of Modena, Largo Pozzo 71, 41124, Modena, Italy.

Amelia Spinella (A)

Department of Rheumatology, Division of Rheumatology, University of Modena and Reggio Emilia, Policlinico of Modena, Largo Pozzo 71, 41124, Modena, Italy.

Sofia Testoni (S)

Department of Rheumatology, Division of Rheumatology, University of Modena and Reggio Emilia, Policlinico of Modena, Largo Pozzo 71, 41124, Modena, Italy.

Melba Lattanzi (M)

Department of Medical and Surgical Sciences, Division of Plastic Surgery, University of Modena and Reggio Emilia, Policlinico of Modena, Largo Pozzo 71, 41124, Modena, Italy.

Raimondo Feminò (R)

Department of Anesthesiology, University of Modena and Reggio Emilia, Policlinico of Modena, Largo Pozzo 71, 41124, Modena, Italy.

Giorgio De Santis (G)

Department of Medical and Surgical Sciences, Division of Plastic Surgery, University of Modena and Reggio Emilia, Policlinico of Modena, Largo Pozzo 71, 41124, Modena, Italy.

Carlo Salvarani (C)

Department of Rheumatology, Division of Rheumatology, University of Modena and Reggio Emilia, Policlinico of Modena, Largo Pozzo 71, 41124, Modena, Italy.

Dilia Giuggioli (D)

Department of Rheumatology, Division of Rheumatology, University of Modena and Reggio Emilia, Policlinico of Modena, Largo Pozzo 71, 41124, Modena, Italy.

Classifications MeSH