Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir.


Journal

IDCases
ISSN: 2214-2509
Titre abrégé: IDCases
Pays: Netherlands
ID NLM: 101634540

Informations de publication

Date de publication:
2021
Historique:
received: 16 09 2021
revised: 03 11 2021
accepted: 04 11 2021
entrez: 29 11 2021
pubmed: 30 11 2021
medline: 30 11 2021
Statut: epublish

Résumé

Among different pathogens, opportunistic viral infection caused by EBV is particularly relevant. This gammaherpesvirus, belonging to the Herpesviridae family, may complicate the disease course in different clinical settings by inducing pathological EBV pictures in patients with a defective immunologic response. Our report evaluated EBV-specific T cell responses by IFN- γ ELISPOT assay, which revealed defective EBV specific immunological response.

Identifiants

pubmed: 34840952
doi: 10.1016/j.idcr.2021.e01331
pii: S2214-2509(21)00287-0
pmc: PMC8605419
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e01331

Informations de copyright

© 2021 The Authors. Published by Elsevier Ltd.

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Auteurs

Caterina Foti (C)

Department of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari "Aldo Moro", Bari, Italy.

Elvira Favoino (E)

Department of Biomedical Science and Human Oncology (DIMO), Rheumatic and Systemic Autoimmune Diseases Unit, University of Bari Medical School, Bari, Italy.

Maria Scarasciulli (M)

Microbiology and Virology Unit - Interdisciplinary Department of Medicine (DIM) - University of Bari "Aldo Moro"- AOU Policlinico Bari, Italy.

Anna Maria Colacicco (AM)

Microbiology and Virology Unit - Interdisciplinary Department of Medicine (DIM) - University of Bari "Aldo Moro"- AOU Policlinico Bari, Italy.

Hamidreza Jahantigh (H)

Interdisciplinary Department of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.

Angela Stufano (A)

Interdisciplinary Department of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.

Piero Lovreglio (P)

Interdisciplinary Department of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.

Paola Mascia (P)

Department of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari "Aldo Moro", Bari, Italy.

Chiara Barlusconi (C)

Department of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari "Aldo Moro", Bari, Italy.

Federico Perosa (F)

Department of Biomedical Science and Human Oncology (DIMO), Rheumatic and Systemic Autoimmune Diseases Unit, University of Bari Medical School, Bari, Italy.

Paolo Romita (P)

Department of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari "Aldo Moro", Bari, Italy.

Agata Calvario (A)

Microbiology and Virology Unit - Interdisciplinary Department of Medicine (DIM) - University of Bari "Aldo Moro"- AOU Policlinico Bari, Italy.

Classifications MeSH