Biologic drugs in chronic spontaneous urticaria.


Journal

Acta bio-medica : Atenei Parmensis
ISSN: 2531-6745
Titre abrégé: Acta Biomed
Pays: Italy
ID NLM: 101295064

Informations de publication

Date de publication:
29 11 2021
Historique:
received: 15 10 2021
accepted: 22 11 2021
entrez: 29 11 2021
pubmed: 30 11 2021
medline: 27 1 2022
Statut: epublish

Résumé

Chronic spontaneous urticaria (CSU) is a condition defined by the presence of recurrent urticaria, angioedema, or both, which persist for more than six weeks in duration and occurs in the absence of an identifiable trigger. Both children and adults can develop CSU, although it is more common in adults and in women than in men, with a peak occurrence in the third to fifth decades of life. It imposes a significant burden on patients, families and healthcare systems. The goal of therapy in patients with CSU is to achieve a level of symptom control and improvement in quality of life that is acceptable to the patient, while minimizing therapy-related side effects. The recent introduction of biologic drugs has changed the management of the disease. This work aims to provide a narrative review of the current state of biological therapy and the promising drugs under development for CSU.

Identifiants

pubmed: 34842589
doi: 10.23750/abm.v92iS7.12415
pmc: PMC9431883
doi:

Substances chimiques

Biological Products 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2021527

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Auteurs

Amelia Licari (A)

1Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy. amelia.licari@unipv.it.

Sara Manti (S)

1UOC Broncopneumologia Pediatrica e Fibrosi Cistica, AOUP "Vittorio-Emanuele", San Marco Hospital, Università di Catania, Catania, Italy. saramanti@hotmail.it.

Salvatore Leonardi (S)

3Department of Clinical and Experimental Medicine, Pediatric Respiratory Unit, San Marco Hospital, University of Catania, Catania, Italy. leonardi@unict.it.

Domenico Minasi (D)

Pediatric Unit Great Metropolitan Hospital Reggio Calabria, Reggio Calabria, Italy. domenico.minasi@tiscali.it.

Carlo Caffarelli (C)

Pediatric Clinic, Department of Medicine and Surgery, Unversity of Parma, Parma, Italy. carlo.caffarelli@unipr.it.

Fabio Cardinale (F)

Department of Pediatrics, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy. fabio.cardinale@libero.it.

Michele Miraglia Del Giudice (M)

Department of Woman, Child and Specialized Surgery, University of Campania "Luigi Vanvitelli. Michele.MIRAGLIADELGIUDICE@unicampania.it.

Mauro Calvani (M)

UOC di Pediatria. Azienda ospedaliera S. Camillo Forlanini, Rome, Italy. maurocalvani58@gmail.com.

Giorgio Ciprandi (G)

Allergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy. giocip@me.com.

Gian Luigi Marseglia (GL)

Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy. gl.marseglia@smatteo.pv.it.

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