Dietary Milk Phospholipids Attenuate Chronic Stress-Induced Changes in Behavior and Endocrine Responses across the Lifespan.
anxiety
chronic stress
diet
hypothalamic-pituitary-adrenal axis
life stages
milk phospholipids
Journal
Molecular nutrition & food research
ISSN: 1613-4133
Titre abrégé: Mol Nutr Food Res
Pays: Germany
ID NLM: 101231818
Informations de publication
Date de publication:
02 2022
02 2022
Historique:
revised:
19
10
2021
received:
12
07
2021
pubmed:
2
12
2021
medline:
1
4
2022
entrez:
1
12
2021
Statut:
ppublish
Résumé
Increasing scientific evidence is validating the use of dietary strategies to support and improve brain health throughout the lifespan, with tailored nutritional interventions catering for specific life stages. Dietary phospholipid supplementations in early life and adulthood are shown to alleviate some of the behavioral consequences associated with chronic stress. This study aims to explore the protective effects of a tailored phospholipid-enriched buttermilk on behavioral and endocrine responses induced by chronic psychosocial stress in adulthood, and to compare these effects according to the life stage at which the supplementation is started. A novel developed phospholipid-enriched dairy product is assessed for its effects on social, anxiety- and depressive-like behaviors, as well as the stress response and cognitive performance following chronic psychosocial stress in C57BL/6J mice, with supplementation beginning in adulthood or early life. Milk phospholipid supplementation from birth protects adult mice against chronic stress-induced changes in endocrine response to a subsequent acute stressor and reduces innate anxiety-like behavior in non-stressed animals. When starting in adulthood, the dietary intervention reverses the anxiety-like phenotype caused by chronic stress exposure. Dairy-derived phospholipids exert differential protective effects against chronic psychosocial stress depending on the targeted life stage and duration of the dietary supplementation.
Identifiants
pubmed: 34851032
doi: 10.1002/mnfr.202100665
doi:
Substances chimiques
Phospholipids
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2100665Informations de copyright
© 2021 Wiley-VCH GmbH.
Références
R. A. H. Adan, E. M. van der Beek, J. K. Buitelaar, J. F. Cryan, J. Hebebrand, S. Higgs, H. Schellekens, S. L. Dickson, Eur. Neuropsychopharmacol. 2019, 29, 1321.
J. Godos, W. Currenti, D. Angelino, P. Mena, S. Castellano, F. Caraci, F. Galvano, D. Del Rio, R. Ferri, G. Grosso, Antioxidants 2020, 9, 346.
C. Lassale, G. D. Batty, A. Baghdadli, F. Jacka, A. Sánchez-Villegas, M. Kivimäki, T. Akbaraly, Mol. Psychiatry 2019, 965.
K. V. Sandhu, E. Sherwin, H. Schellekens, C. Stanton, T. G. Dinan, J. F. Cryan, Transl. Res. 2017, 179, 223.
A. J. Forgie, K. M. Drall, S. L. Bourque, C. J. Field, A. L. Kozyrskyj, B. P. Willing, BMC Med. 2020, 18, 135.
C. M. Hueston, J. F. Cryan, Y. M. Nolan, Transl. Psychiatry 2017, 7, e1081.
M. Koopman, J. K. Daniels, C. Spitzer, A. Lampe, S. El Aidy, Curr. Opin. Psychiatry 2017, 30, 369.
A. Di Ciaula, P. Portincasa, Mech. Ageing Dev. 2020, 111244.
M. Schverer, S. M. O'Mahony, K. J. O'Riordan, F. Donoso, B. L. Roy, C. Stanton, T. G. Dinan, H. Schellekens, J. F. Cryan, Neurosci. Biobehav. Rev. 2020, 111, 183.
H. Watson, Essays Biochem. 2015, 59, 43.
I. H. Mather, in Encyclopedia of Dairy Sciences, 2nd ed. (Eds: J. Fuquay, P. Fox, P. McSweeney), Elsevier L, San diego 2011, pp. 680-690.
P. Monteleone, M. Maj, L. Beinat, M. Natale, D. Kemali, Eur. J. Clin. Pharmacol. 1992, 41, 385.
M. Schubert, C. Contreras, N. Franz, J. Hellhammer, Nutr. Res. 2011, 31, 413.
N. B. Boyle, L. Dye, K. Arkbåge, L. Thorell, P. Frederiksen, F. Croden, C. Lawton, Nutrition 2019, 57, 183.
J. Hellhammer, A. R. Waladkhani, T. Hero, C. Buss, Br. Food J. 2010, 112, 1124.
J. Hellhammer, E. Fries, C. Buss, V. Engert, A. Tuch, D. Rutenberg, D. Hellhammer, Stress 2004, 7, 119.
T. Kanno, Y. Jin, T. Nishizaki, Behav. Pharmacol. 2014, 25, 575.
J. J. Strain, World J. Biol. Psychiatry 2018, 19, S14.
P. A. Zunszain, C. Anacker, A. Cattaneo, L. A. Carvalho, C. M. Pariante, Prog. Neuro-Psychopharmacol. Biol. Psychiatry 2011, 35, 722.
P. V. Dixit, R. Sahu, D. K. Mishra, J. Pharmacol. Toxicol. Methods 2020, 102, 102.
B. C. Finger, T. G. Dinan, J. F. Cryan, Psychoneuroendocrinology 2012, 37, 729.
S. H. House, Nutr. Health 2007, 19, 143.
S. Kivity, M. T. Arango, N. Molano-González, M. Blank, Y. Shoenfeld, Immunol. Res. 2017, 65, 99.
B. C. Finger, T. G. Dinan, J. F. Cryan, Neuroscience 2011, 192, 351.
M. Tramullas, T. G. Dinan, J. F. Cryan, Stress 2012, 15, 281.
M. van de Wouw, M. Boehme, J. M. Lyte, N. Wiley, C. Strain, O. O'Sullivan, G. Clarke, C. Stanton, T. G. Dinan, J. F. Cryan, J. Physiol. 2018, 596, 4923.
A. Burokas, S. Arboleya, R. D. Moloney, V. L. Peterson, K. Murphy, G. Clarke, C. Stanton, T. G. Dinan, J. F. Cryan, Biol. Psychiatry 2017, 82, 472.
K. M. Barry, T. G. Dinan, P. M. Kelly, Innovative Food Sci. Emerging Technol. 2017, 41, 301.
J. Kumar, J. C. Chuang, E. S. Na, A. Kuperman, A. G. Gillman, S. Mukherjee, J. M. Zigman, C. A. McClung, M. Lutter, Appetite 2013, 64, 81.
M. Razzoli, V. Sanghez, A. Bartolomucci, Frontiers in Nutrition 2015, 30.
C. P. Müller, M. Reichel, C. Mühle, C. Rhein, E. Gulbins, J. Kornhuber, Biochim. Biophys. Acta, Mol. Cell Biol. Lipids 2015, 1851, 1052.
A. Demirkan, A. Isaacs, P. Ugocsai, G. Liebisch, M. Struchalin, I. Rudan, J. F. Wilson, P. P. Pramstaller, U. Gyllensten, H. Campbell, G. Schmitz, B. A. Oostra, C. M. van Duijn, J. Psychiatr. Res. 2013, 47, 357.
A. A. Walf, C. A. Frye, Nat. Protoc. 2007, 2, 322.
M. La-Vu, B. C. Tobias, P. J. Schuette, A. Adhikari, Front. Behav. Neurosci. 2020, 14, 145.
I. Carrié, M. Clément, D. De Javel, H. Francès, J. M. Bourre, J. Lipid Res. 2000, 41, 473.
D. A. Slattery, J. F. Cryan, Nat. Protoc. 2012, 7, 1009.
L. Schipper, G. van Dijk, L. M. Broersen, M. Loos, N. Bartke, A. J. Scheurink, E. M. van der Beek, J. Nutr. 2016, 146, 1155.
M. A. Starks, S. L. Starks, M. Kingsley, M. Purpura, R. Jäger, J. Int. Soc. Sports Nutr. 2008, 5.
S. M. O'Mahony, K.-A. McVey Neufeld, R. V. Waworuntu, M. M. Pusceddu, S. Manurung, K. Murphy, C. Strain, M. C. Laguna, V. L. Peterson, C. Stanton, B. M. Berg, T. G. Dinan, J. F. Cryan, European Journal of Neuroscience 2020, 51, 1042.
T. Cerdó, E. Diéguez, C. Campoy, Am. J. Physiol. 2019, 317, E617 .
E. L. Prado, K. G. Dewey, Nutr. Rev. 2014, 72, 267.