Effect of sequential eradication therapy on serum osteoprotegerin levels in patients with

Eradication Helicobacter pylori bone alkaline phosphatase fecal calprotectin inflammatory bowel disease osteoprotegerin

Journal

The Journal of international medical research
ISSN: 1473-2300
Titre abrégé: J Int Med Res
Pays: England
ID NLM: 0346411

Informations de publication

Date de publication:
Nov 2021
Historique:
entrez: 1 12 2021
pubmed: 2 12 2021
medline: 15 12 2021
Statut: ppublish

Résumé

To investigate the effect of sequential Three groups of patients were involved in this observational cross-sectional study: IBD (n = 83), Serum osteoprotegerin levels were significantly correlated with the simple endoscopic score for Crohn's disease and Mayo score for ulcerative colitis. The receiver operating characteristic analysis of osteoprotegerin revealed high values for the area under the curve, sensitivity, and specificity. Discriminant analysis illustrated that osteoprotegerin levels significantly differentiated patients with IBD from healthy controls. Osteoprotegerin and FC levels distinguished the IBD and HP + IBD groups from the NC and HP groups. Sequential eradication therapy did not affect serum osteoprotegerin levels in patients with

Identifiants

pubmed: 34851775
doi: 10.1177/03000605211060648
pmc: PMC8647270
doi:

Substances chimiques

Osteoprotegerin 0

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

3000605211060648

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Auteurs

Hussam Murad (H)

Department of Pharmacology, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia.
Department of Pharmacology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Misbahuddin Rafeeq (M)

Department of Pharmacology, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia.

Mahmoud Mosli (M)

Department of Medicine, Division of Gastroenterology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Mamdouh Gari (M)

Department of Hematology, Faculty of Applied Medical Sciences, 37848King Abdulaziz University, King Abdulaziz University, Jeddah, Saudi Arabia.

Mohammed Basheikh (M)

Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

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