Selecting the Antigen.

Animals Antibodies, Monoclonal Antibody Formation Antigens

Journal

Cold Spring Harbor protocols
ISSN: 1559-6095
Titre abrégé: Cold Spring Harb Protoc
Pays: United States
ID NLM: 101524530

Informations de publication

Date de publication:
01 12 2021
Historique:
entrez: 2 12 2021
pubmed: 3 12 2021
medline: 23 4 2022
Statut: epublish

Résumé

The classical method for generating polyclonal or monoclonal antibodies relies on the in vivo humoral response of animals. Here we describe the factors that antigens can have that might influence the strength and quality of an antibody response. This introduction is divided into three sections: (1) an overview of immunogenicity, (2) choosing the best form for the immunogen, and (3) methods for modifying antigens to make them more immunogenic.

Identifiants

DOI: 10.1101/pdb.top099945 PMID: 34853124
pubmed: 34853124
pii: 2021/12/pdb.top099945
doi: 10.1101/pdb.top099945
doi:

Substances chimiques

Antibodies, Monoclonal 0
Antigens 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2021 Cold Spring Harbor Laboratory Press.

Auteurs

Edward A Greenfield (EA)

James DeCaprio (J)

Mohan Brahmandam (M)

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Selecting the Antigen.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Anticorps monoclonaux › Selecting the Antigen.
questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Immunité acquise › Immunité active › Production d'anticorps › Selecting the Antigen.
questionsmedicales.fr › Facteurs biologiques › Antigènes › Selecting the Antigen.