Prognostic value of baseline metabolic tumour volume in advanced-stage Hodgkin's lymphoma.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
01 12 2021
Historique:
received: 11 08 2021
accepted: 17 11 2021
entrez: 2 12 2021
pubmed: 3 12 2021
medline: 19 1 2022
Statut: epublish

Résumé

Our aim was to evaluate the prognostic value of initial total metabolic tumour volume (TMTV) in a population of patients with advanced-stage Hodgkin's lymphoma (HL). We retrospectively included 179 patients with stage IIb-III-IV Hodgkin's disease who received BEACOPP or ABVD as the first-line treatment. The initial TMTV was determined using a semi-automatic method for each patient. We analysed its prognostic value in terms of 5-year progression-free survival (PFS), overall survival, and positron emission tomography (PET) response after two courses of chemotherapy. Considering all the treatments and using a threshold of 217 cm

Identifiants

pubmed: 34853386
doi: 10.1038/s41598-021-02734-w
pii: 10.1038/s41598-021-02734-w
pmc: PMC8636481
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

23195

Informations de copyright

© 2021. The Author(s).

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Auteurs

Pierre Pinochet (P)

Nuclear Medicine Department, Henri Becquerel Cancer Centre, Rue d'Amiens, Rouen, France.
QuantiF-LITIS (EA 4108-FR CNRS 3638), Faculty of Medicine, University of Rouen, Rouen, France.

Edgar Texte (E)

Nuclear Medicine Department, Henri Becquerel Cancer Centre, Rue d'Amiens, Rouen, France.
QuantiF-LITIS (EA 4108-FR CNRS 3638), Faculty of Medicine, University of Rouen, Rouen, France.

Aspasia Stamatoullas-Bastard (A)

Hematology Department, Henri Becquerel Cancer Centre, Rouen, France.
INSERM U1245, Henri Becquerel Cancer Centre, Rouen, France.

Pierre Vera (P)

Nuclear Medicine Department, Henri Becquerel Cancer Centre, Rue d'Amiens, Rouen, France.
QuantiF-LITIS (EA 4108-FR CNRS 3638), Faculty of Medicine, University of Rouen, Rouen, France.

Sorina-Dana Mihailescu (SD)

Department of Statistics and Clinical Research Unit, Henri Becquerel Cancer Centre, Rouen, France.

Stéphanie Becker (S)

Nuclear Medicine Department, Henri Becquerel Cancer Centre, Rue d'Amiens, Rouen, France. stephanie.becker@chb.unicancer.fr.
QuantiF-LITIS (EA 4108-FR CNRS 3638), Faculty of Medicine, University of Rouen, Rouen, France. stephanie.becker@chb.unicancer.fr.

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Classifications MeSH