What can 7T sodium MRI tell us about cellular energy depletion and neurotransmission in Alzheimer's disease?
Alzheimer's disease
magnetic resonance imaging
positron emission tomography
sodium (23Na) MRI
tau
Journal
Alzheimer's & dementia : the journal of the Alzheimer's Association
ISSN: 1552-5279
Titre abrégé: Alzheimers Dement
Pays: United States
ID NLM: 101231978
Informations de publication
Date de publication:
11 2021
11 2021
Historique:
revised:
09
08
2021
received:
03
03
2021
accepted:
22
09
2021
pubmed:
3
12
2021
medline:
5
2
2022
entrez:
2
12
2021
Statut:
ppublish
Résumé
The pathophysiological processes underlying the development and progression of Alzheimer's disease (AD) on the neuronal level are still unclear. Previous research has hinted at metabolic energy deficits and altered sodium homeostasis with impaired neuronal function as a potential metabolic marker relevant for neurotransmission in AD. Using sodium (
Substances chimiques
Carbolines
0
tau Proteins
0
Sodium
9NEZ333N27
7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole
J09QS3Z3WB
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1843-1854Informations de copyright
© 2021 the Alzheimer's Association.
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