Use-dependent corticospinal excitability is associated with resilience and physical performance during simulated military operational stress.
motor cortex
physical activity
resilience
transcranial magnetic stimulation
use-dependent plasticity
Journal
Journal of applied physiology (Bethesda, Md. : 1985)
ISSN: 1522-1601
Titre abrégé: J Appl Physiol (1985)
Pays: United States
ID NLM: 8502536
Informations de publication
Date de publication:
01 01 2022
01 01 2022
Historique:
pubmed:
3
12
2021
medline:
1
2
2022
entrez:
2
12
2021
Statut:
ppublish
Résumé
Simulated military operational stress (SMOS) provides a useful model to better understand resilience in humans as the stress associated with caloric restriction, sleep deficits, and fatiguing exertion degrades physical and cognitive performance. Habitual physical activity may confer resilience against these stressors by promoting favorable use-dependent neuroplasticity, but it is unclear how physical activity, resilience, and corticospinal excitability (CSE) relate during SMOS. To examine associations between corticospinal excitability, physical activity, and physical performance during SMOS. Fifty-three service members (age: 26 ± 5 yr, 13 women) completed a 5-day and -night intervention composed of familiarization, baseline, SMOS (2 nights/days), and recovery days. During SMOS, participants performed rigorous physical and cognitive activities while receiving half of normal sleep (two 2-h blocks) and caloric requirements. Lower and upper limb CSE were determined with transcranial magnetic stimulation (TMS) stimulus-response curves. Self-reported resilience, physical activity, military-specific physical performance (TMT), and endocrine factors were compared in individuals with high (HIGH) and low CSE based on a median split of lower limb CSE at baseline. HIGH had greater physical activity and better TMT performance throughout SMOS. Both groups maintained physical performance despite substantial psychophysiological stress. Physical activity, resilience, and TMT performance were directly associated with lower limb CSE. Individual differences in physical activity coincide with lower (but not upper) limb CSE. Such use-dependent corticospinal excitability directly relates to resilience and physical performance during SMOS. Future studies may use noninvasive neuromodulation to clarify the interplay among CSE, physical activity, and resilience and improve physical and cognitive performance.
Identifiants
pubmed: 34855522
doi: 10.1152/japplphysiol.00628.2021
pmc: PMC8791840
doi:
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
187-198Références
Neurosci Biobehav Rev. 2013 May;37(4):573-84
pubmed: 23415701
Ann Neurol. 1993 Jul;34(1):33-7
pubmed: 8517678
Clin Neurophysiol. 2012 May;123(5):858-82
pubmed: 22349304
Exp Brain Res. 2021 Apr;239(4):1099-1110
pubmed: 33547521
Ann Neurol. 1995 Dec;38(6):910-5
pubmed: 8526463
Nat Rev Neurosci. 2008 Jan;9(1):58-65
pubmed: 18094706
J Physiol. 2009 Dec 15;587(Pt 24):5831-42
pubmed: 19858227
Physiol Rev. 2007 Jul;87(3):873-904
pubmed: 17615391
Med Sci Sports Exerc. 2011 Aug;43(8):1575-81
pubmed: 21681120
Psychol Assess. 2017 May;29(5):479-485
pubmed: 27504904
Sleep Med. 2013 Mar;14(3):288-92
pubmed: 23343775
J Appl Physiol (1985). 2017 Aug 1;123(2):364-374
pubmed: 28495848
Nat Rev Neurosci. 2009 Jun;10(6):446-57
pubmed: 19455174
Brain Connect. 2020 Mar;10(2):53-71
pubmed: 32093486
J Strength Cond Res. 2021 May 1;35(5):1296-1305
pubmed: 33780395
Brain. 1993 Feb;116 ( Pt 1):39-52
pubmed: 8453464
Neuropsychopharmacology. 2004 Mar;29(3):598-604
pubmed: 14647485
Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3661-5
pubmed: 10716702
Med Sci Sports Exerc. 2000 Sep;32(9 Suppl):S498-504
pubmed: 10993420
Biol Psychiatry. 2013 Jan 1;73(1):70-4
pubmed: 22840760
PLoS One. 2017 Mar 9;12(3):e0173672
pubmed: 28278300
J Clin Neurophysiol. 2014 Jun;31(3):246-52
pubmed: 24887609
Physiol Behav. 2016 Oct 15;165:86-97
pubmed: 27374427
Neuroscience. 2020 Jun 15;437:242-255
pubmed: 32482330
J Physiol. 2008 Jan 1;586(1):65-70
pubmed: 17717010
Med Sci Sports Exerc. 2002 Nov;34(11):1814-22
pubmed: 12439088
Neuroimage. 2007 Jul 15;36(4):1277-87
pubmed: 17524675
Exp Physiol. 2014 Aug;99(8):1053-64
pubmed: 24907029
Physiol Behav. 2015 Nov 1;151:279-83
pubmed: 26253211
Sci Rep. 2019 Dec 16;9(1):19212
pubmed: 31844115
J Electromyogr Kinesiol. 2000 Oct;10(5):361-74
pubmed: 11018445
Brain Res. 2021 Mar 2;1761:147395
pubmed: 33662340
Trends Cogn Sci. 2011 Dec;15(12):576-84
pubmed: 22078931
Med Sci Sports Exerc. 1993 Jan;25(1):71-80
pubmed: 8292105
Exp Physiol. 2020 Jul;105(7):1132-1150
pubmed: 32363636
J Psychiatr Res. 2015 Jun;65:146-53
pubmed: 25881517
Neurobiol Aging. 2014 Sep;35 Suppl 2:S20-8
pubmed: 24952993
Psychopharmacology (Berl). 2002 Nov;164(3):250-61
pubmed: 12424548
Eur J Appl Physiol Occup Physiol. 1982;49(3):389-99
pubmed: 6754371
Physiol Rep. 2019 Jun;7(11):e14140
pubmed: 31175708
J Appl Physiol (1985). 2005 Oct;99(4):1558-68
pubmed: 15890749
Exp Brain Res. 2015 Mar;233(3):679-89
pubmed: 25563496
Med Sci Sports Exerc. 1982;14(5):377-81
pubmed: 7154893
Front Behav Neurosci. 2016 Jul 19;10:150
pubmed: 27486391
J Acad Nutr Diet. 2017 Mar;117(3):396-403
pubmed: 27825793
Sleep. 2006 Dec;29(12):1595-8
pubmed: 17252890
Eur J Appl Physiol. 2021 Mar;121(3):697-706
pubmed: 33389143
Nat Hum Behav. 2017 Nov;1(11):784-790
pubmed: 31024125
Neuropsychologia. 1998 Jan;36(1):37-43
pubmed: 9533385
Cereb Cortex. 2019 Jan 1;29(1):356-371
pubmed: 30364930
J Endocrinol Invest. 2008 Jul;31(7):587-91
pubmed: 18787373
Brain Res. 2006 Nov 22;1121(1):59-65
pubmed: 17010953
J Appl Physiol (1985). 2013 Feb 15;114(4):429-35
pubmed: 23239871
J Neurophysiol. 2019 Jul 1;122(1):241-250
pubmed: 31091158
Brain Stimul. 2010 Jul;3(3):131-9
pubmed: 20633442
Ann N Y Acad Sci. 2016 Jun;1373(1):56-64
pubmed: 26919273
Exp Physiol. 2009 Oct;94(10):1062-9
pubmed: 19666694
Neuropsychologia. 1971 Mar;9(1):97-113
pubmed: 5146491
Physiol Behav. 2021 Jul 1;236:113413
pubmed: 33811909
J Neurophysiol. 1995 Sep;74(3):1037-45
pubmed: 7500130
Depress Anxiety. 2003;18(2):76-82
pubmed: 12964174
J Neurophysiol. 1998 Feb;79(2):1117-23
pubmed: 9463469
Nature. 2002 Feb 7;415(6872):640-4
pubmed: 11807497
Ann N Y Acad Sci. 2004 Dec;1032:1-7
pubmed: 15677391
Exp Brain Res. 2000 Jan;130(2):238-43
pubmed: 10672477
Lancet. 1985 May 11;1(8437):1106-7
pubmed: 2860322
Eur J Appl Physiol. 2021 Mar;121(3):707-719
pubmed: 33389142