Racialized Economic Segregation and Breast Cancer Mortality among Women in Maryland.
Journal
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
ISSN: 1538-7755
Titre abrégé: Cancer Epidemiol Biomarkers Prev
Pays: United States
ID NLM: 9200608
Informations de publication
Date de publication:
02 2022
02 2022
Historique:
received:
29
07
2021
revised:
11
10
2021
accepted:
01
12
2021
pubmed:
5
12
2021
medline:
9
3
2022
entrez:
4
12
2021
Statut:
ppublish
Résumé
Our objective was to determine the association between racialized economic segregation and the hazard of breast cancer mortality in Maryland. Among 35,066 women (24,540 White; 10,526 Black) diagnosed with incident invasive breast cancer in Maryland during 2007 to 2017, exposure to racialized economic segregation was measured at the census tract level using Index of Concentration at the Extremes metrics. HRs and 95% confidence intervals (CI) were estimated using Cox proportional hazards regression for the association between racialized economic segregation and the hazard of breast cancer mortality, accounting for clustering at the census tract level. Models were adjusted for age and stratified by race, median age (<60 years, ≥60 years), and clinical characteristics. Overall, the hazard of breast cancer mortality was 1.84 times as high (95% CI, 1.64-2.06) for the least privileged quintile of racialized economic segregation compared with the most privileged quintile. This association differed significantly ( Our results suggest that breast cancer survival disparities exist in Maryland among women residing in the least privileged census tracts with lower income households and higher proportions of Black residents. Our findings provide new insights into the breast cancer mortality disparities observed among women in Maryland.
Sections du résumé
BACKGROUND
Our objective was to determine the association between racialized economic segregation and the hazard of breast cancer mortality in Maryland.
METHODS
Among 35,066 women (24,540 White; 10,526 Black) diagnosed with incident invasive breast cancer in Maryland during 2007 to 2017, exposure to racialized economic segregation was measured at the census tract level using Index of Concentration at the Extremes metrics. HRs and 95% confidence intervals (CI) were estimated using Cox proportional hazards regression for the association between racialized economic segregation and the hazard of breast cancer mortality, accounting for clustering at the census tract level. Models were adjusted for age and stratified by race, median age (<60 years, ≥60 years), and clinical characteristics.
RESULTS
Overall, the hazard of breast cancer mortality was 1.84 times as high (95% CI, 1.64-2.06) for the least privileged quintile of racialized economic segregation compared with the most privileged quintile. This association differed significantly (
CONCLUSIONS
Our results suggest that breast cancer survival disparities exist in Maryland among women residing in the least privileged census tracts with lower income households and higher proportions of Black residents.
IMPACT
Our findings provide new insights into the breast cancer mortality disparities observed among women in Maryland.
Identifiants
pubmed: 34862211
pii: 1055-9965.EPI-21-0923
doi: 10.1158/1055-9965.EPI-21-0923
pmc: PMC8825681
mid: NIHMS1765973
doi:
Types de publication
Comparative Study
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
413-421Subventions
Organisme : NCI NIH HHS
ID : P30 CA006973
Pays : United States
Organisme : NIMH NIH HHS
ID : R25 MH083620
Pays : United States
Organisme : NCI NIH HHS
ID : T32 CA009314
Pays : United States
Informations de copyright
©2021 American Association for Cancer Research.
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