Tuberculosis trend among native and foreign-born people over a 17 year period (2004-2020) in a large province in Northern Italy.
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Child
Child, Preschool
Emigrants and Immigrants
/ statistics & numerical data
Female
Humans
Incidence
Infant
Infant, Newborn
Italy
/ epidemiology
Male
Middle Aged
Poisson Distribution
Retrospective Studies
Risk Factors
Sex Factors
Tuberculosis, Pulmonary
/ epidemiology
Young Adult
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
03 12 2021
03 12 2021
Historique:
received:
11
08
2021
accepted:
16
11
2021
entrez:
4
12
2021
pubmed:
5
12
2021
medline:
15
12
2021
Statut:
epublish
Résumé
Tuberculosis (TB) incidence should decline by 20% in the Europe in 2015-2020, in line with End-TB milestones. We retrospectively evaluated TB notifications in the province of Brescia from 2004 to 2020. Cases were classified per patient origin and entitlement to Health Assistance for foreign born people: Italians (ITA), Foreigners permanently entitled (PEF) or Temporarily Entitled (TEF) to Health Regional Assistance. Poisson regression analysis was performed to assess associations between incidence and age, sex, continent of origin and year of notification. Overall 2279 TB cases were notified: 1290 (56.6%) in PEF, 700 (30.7%) in ITA and 289 (12.7%) in TEF. Notifications declined from 15.2/100,000 in 2004 to 6.9/100,000 in 2020 (54.6% reduction, temporary increase in 2013-2018 for TEF). Age (Incidence Risk Ratio, IRR, 1.02, 1.019-1.024 95%CI), sex (IRR 1.22, 1.12-1.34 95%CI), and continent of origin were positively associated with notifications (IRR 34.8, 30.8-39.2 95%CI for Asiatic, and IRR 20.6, 18.1-23.4 95%CI for African origin), p < 0.001. Notification decline was sharper in 2020, especially among TEF. End-TB milestone for 2020 was reached, but foreigners continue to represent a high risk group for the disease. Discontinuation of services due to the COVID-19 pandemic was associated with a sharp decrease in TB notification in 2020.
Identifiants
pubmed: 34862409
doi: 10.1038/s41598-021-02540-4
pii: 10.1038/s41598-021-02540-4
pmc: PMC8642384
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
23394Informations de copyright
© 2021. The Author(s).
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